Transcranial Magnetic Stimulation (TMS) for CRPS
1 other identifier
interventional
20
1 country
1
Brief Summary
The purpose of this pilot study is to test the durability of response to Transcranial Magnetic Stimulation (TMS) for the symptoms of Complex Regional Pain Syndrome (CRPS). The investigators will test various methods of TMS for varying lengths of time in a pilot study to investigate what the clinical impact.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2014
CompletedFirst Submitted
Initial submission to the registry
February 13, 2014
CompletedFirst Posted
Study publicly available on registry
February 20, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2015
CompletedResults Posted
Study results publicly available
May 15, 2017
CompletedMay 15, 2017
May 1, 2017
1 year
February 13, 2014
April 3, 2017
May 11, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Present Pain Intensity
Present pain intensity was reported by participants using a visual analog scale (VAS) from scores ranging from 1-10; lower scores represent less pain, higher scores represent more severe pain.
Baseline, post-treatment, one week follow-up
Study Arms (2)
TMS Intervention for 5 days
EXPERIMENTALApplication of Transcranial Magnetic Stimulation (TMS) for up to 5 days
TMS Intervention for 1 day
EXPERIMENTALApplication of Transcranial Magnetic Stimulation (TMS) for 1 day
Interventions
Eligibility Criteria
You may qualify if:
- Age 18 or older
- Diagnosis of CRPS (complex regional pain syndrome)
- Average pain level reported on Numerical Rating Scale meets entry criteria
- Ability to perform the experimental task and procedures.
You may not qualify if:
- MRI contraindication (metal implants or devices, claustrophobia)
- TMS Contraindication (eg metal implant or devices near the site of stimulation)
- History of epilepsy
- History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher.
- Neurologic illness that would interfere with brain integrity
- Current medical condition or medication use that would interfere with study procedures or data integrity, at the discretion of the researcher.
- Currently pregnant or planning to become pregnant.
- On going legal action or disability claim.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Stanford University School of Medicine
Palo Alto, California, 94304, United States
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Sean Mackey, Chief, Division of Pain Medicine, Director, Stanford Systems Neuroscience and Pain Lab
- Organization
- Stanford University School of Medicine
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Chief, Division of Pain Medicine
Study Record Dates
First Submitted
February 13, 2014
First Posted
February 20, 2014
Study Start
February 1, 2014
Primary Completion
February 1, 2015
Study Completion
March 1, 2015
Last Updated
May 15, 2017
Results First Posted
May 15, 2017
Record last verified: 2017-05