NCT02065583

Brief Summary

This study will measure the accuracy of a disposable, non-invasive device for the continuous monitoring of abdominal sounds, called the AGIS sensor (Acoustic Gastro-Intestinal Surveillance) in predicting patients' intolerance to feeding (defined as severe nausea, vomiting, or need to place a nasogastric tube within 4 hours of initiating a standard feeding protocol) following abdominal surgery. This will be a pragmatic, observational study.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2013

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

December 20, 2013

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 19, 2014

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2018

Completed
Last Updated

December 11, 2015

Status Verified

December 1, 2015

Enrollment Period

4.1 years

First QC Date

December 20, 2013

Last Update Submit

December 9, 2015

Conditions

Keywords

IleusEquipment and SuppliesTechnologyAcoustics

Outcome Measures

Primary Outcomes (1)

  • Count of motility events per minute.

    The primary unit of analysis will be the number of motility events registered by the AGIS sensor per minute.

    1 minute

Study Arms (1)

GI abdominal surgery patients

Patients recovering from gastrointestinal abdominal surgery.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The investigators will recruit patients who are scheduled for GI abdominal surgery at Cedars-Sinai Medical Center

You may qualify if:

  • years of age or older
  • Patient scheduled to undergo abdominal surgery

You may not qualify if:

  • Cannot consent or has no surrogate who can consent.
  • Cognitive inability to follow directions to maintain abdominal device in place
  • Any abdominal wall condition that disallows topical coverage as deemed by the managing surgeons (e.g. open abdominal wound, oozing wound, advanced cellulitis, necrotizing fasciitis, etc)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States

RECRUITING

Related Publications (1)

  • Kaneshiro M, Kaiser W, Pourmorady J, Fleshner P, Russell M, Zaghiyan K, Lin A, Martinez B, Patel A, Nguyen A, Singh D, Zegarski V, Reid M, Dailey F, Xu J, Robbins K, Spiegel B. Postoperative Gastrointestinal Telemetry with an Acoustic Biosensor Predicts Ileus vs. Uneventful GI Recovery. J Gastrointest Surg. 2016 Jan;20(1):132-9; discussion 139. doi: 10.1007/s11605-015-2956-3. Epub 2015 Sep 25.

MeSH Terms

Conditions

Ileus

Condition Hierarchy (Ancestors)

Intestinal ObstructionIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Study Officials

  • Brennan Spiegel, MD, MSHS

    Cedars-Sinai Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jennifer Talley, MSPH

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, Health Services Research

Study Record Dates

First Submitted

December 20, 2013

First Posted

February 19, 2014

Study Start

December 1, 2013

Primary Completion

January 1, 2018

Study Completion

January 1, 2018

Last Updated

December 11, 2015

Record last verified: 2015-12

Locations