NCT02059005

Brief Summary

This study will assess Specialized Community Disease Management (SCDM), an intervention which employs various evidence-based strategies to engage substance using co-morbid patients while in the hospital and follow them into the community via an empirically validated telephone approach as well as contact with a trained community health worker peer specialist. The investigators will first adapt and refine the core SCDM intervention with patient, provider, and stakeholder input through an active community advisory board. The investigators will then conduct a three-year, randomized controlled trial of 222 patients enrolled prior to hospital discharge who are diagnosed with congestive heart failure, pneumonia, acute myocardial infarction, chronic obstructive pulmonary disease, diabetes mellitus, or end-stage renal disease, and a substance use disorder (SUD). Patients will be randomized to either the SCDM intervention or Treatment as Usual (TAU), in which a team of nurse navigators and community health workers follow patients (primarily by telephone) for 90 days post-discharge, but do not address the specific needs of SUDs. The investigators will test the following four hypotheses: (1) patients randomized to SCDM will demonstrate larger reductions in substance use measured by urine-confirmed self-reported days using over the 6-month follow-up compared to patients randomized to TAU, (2) patients randomized to SCDM will attend more specialty substance abuse intervention and treatment sessions over the 6 month follow-up than patients randomized to TAU, (3) patients randomized to SCDM will demonstrate reduced HIV transmission risk behaviors and greater rates of HIV testing over the 6 month follow-up than patients randomized to TAU, and (4) patients randomized to SCDM will experience fewer days of rehospitalization and use of acute emergency services than patients randomized to TAU.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
97

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2014

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 7, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 11, 2014

Completed
9 months until next milestone

Study Start

First participant enrolled

November 18, 2014

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 16, 2017

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

February 28, 2017

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

August 10, 2018

Completed
Last Updated

March 29, 2023

Status Verified

March 1, 2023

Enrollment Period

2.2 years

First QC Date

February 7, 2014

Results QC Date

May 24, 2017

Last Update Submit

March 27, 2023

Conditions

Keywords

AddictionSubstance Use DisorderRehospitalizationCommunity Disease ManagementBehavioral HealthCommunity Health Worker

Outcome Measures

Primary Outcomes (1)

  • Change in Substance Use Rates From Baseline

    Urinalysis confirmed self-reported days of use for any substance, including alcohol, cocaine, marijuana, opiates, sedatives, and hallucinogens over time. Participants reported substance use for the 90 days prior to the assessment date.

    0, 3, 6 months

Secondary Outcomes (2)

  • Change in Treatment Session Attendance From Baseline

    0, 3, 6, months

  • Number of Hospitalizations and Use of Emergency Services

    0, 3, 6, months

Study Arms (2)

Specialized Community Disease Management

EXPERIMENTAL

Specialized Community Disease Management

Behavioral: Specialized Community Disease Management

Treatment As Usual

ACTIVE COMPARATOR

Treatment as Usual: standard post-hospital discharge with medical monitoring.

Behavioral: Treatment As Usual

Interventions

Specialized Community Disease Management is 90-day program that employs specialized teams including a trained clinical social worker and a peer-specialist community health worker who provide evidence-based telephone continuing care, home visits, and focus on patients' substance use following hospital discharge.

Specialized Community Disease Management

Treatment as Usual is a 90-day, post-discharge program that consists of medical monitoring by nurses and community health workers who have no special training in working with substance use disorder patients, and does not address substance use.

Treatment As Usual

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patient is 18 years or older
  • alcohol and/or drug screening score that indicates at least mild problem severity

You may not qualify if:

  • medical or psychiatric complications
  • patient was admitted to hospital directly from a drug and alcohol inpatient rehabilitation facility
  • patient reports plans to leave the area within the next 12 months
  • patient is unable to provide valid informed consent
  • patient is attending dialysis
  • patient is not English-speaking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States

Location

Related Links

MeSH Terms

Conditions

Alcohol DrinkingHeart FailurePneumoniaDiabetes MellitusPulmonary Disease, Chronic ObstructiveKidney Failure, ChronicBehavior, AddictiveSubstance-Related Disorders

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Drinking BehaviorBehaviorHeart DiseasesCardiovascular DiseasesRespiratory Tract InfectionsInfectionsLung DiseasesRespiratory Tract DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesLung Diseases, ObstructiveChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsRenal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesCompulsive BehaviorImpulsive BehaviorChemically-Induced DisordersMental Disorders

Results Point of Contact

Title
Adam Brooks, PhD
Organization
Treatment Research Institute

Study Officials

  • Adam C Brooks, PhD

    Treatment Research Institute

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 7, 2014

First Posted

February 11, 2014

Study Start

November 18, 2014

Primary Completion

February 16, 2017

Study Completion

February 28, 2017

Last Updated

March 29, 2023

Results First Posted

August 10, 2018

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will share

in line with HIPAA protections, we will make our final dataset available to other researchers. Fully de-identified data will be available to any researcher. If a researcher should request a limited dataset then we will only share that data after obtaining an appropriate data use agreement which includes an agreement not to attempt to re-identify or contact participants. We will not share directly identifiable data with outside researchers per our HIPAA authorization for this study.

Locations