NCT02049463

Brief Summary

Purpose: To investigate the different sound spectrum of carotid arteries and to analyze its relationship to the vessel disease, and to build a new biomarker about vascular disorder. Methods: To record the carotid phonoangiography with digital stereoscopy and analysis the spectrum with different algorithm such as FFT, wavelet, entropy, complexity, and HHT. The results will be correlated and comparison to the finding in clinical, carotid Doppler and duplex, CTA, MR, and catheter angiography. Statistics: The significance of difference between parameters was computed using t-tests or paired t-test etc. A p value \<0.05 is defined as significant.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2014

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 28, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 30, 2014

Completed
2 days until next milestone

Study Start

First participant enrolled

February 1, 2014

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2016

Completed
Last Updated

January 30, 2014

Status Verified

January 1, 2014

Enrollment Period

2 years

First QC Date

January 28, 2014

Last Update Submit

January 29, 2014

Conditions

Carotid AtherosclerosisSeeing Sounds as ColorsStenosisStroke

Keywords

carotid arterysoundstenosiswallstroke

Outcome Measures

Primary Outcomes (1)

  • progression of stenosis

    Follow-up the severity of the carotid stenosis and correlate its wall change

    three years

Secondary Outcomes (1)

  • wall change

    three years

Eligibility Criteria

Age20 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

the patients who is going to have carotid angiography study and with informed consent signed.

You may qualify if:

  • Age: 20 years old to 99 years old
  • Gender: Unlimited
  • Because different types of brain diseases, those who received conventional catheter vascular examination.

You may not qualify if:

  • Neck inflammation locally who can not admit the sound.
  • Due to inability to cooperate to accept those recordings.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hon-Man Liu

Dawan, Taiwan, 10002, Taiwan

Location

MeSH Terms

Conditions

Carotid Artery DiseasesConstriction, PathologicStroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Hon-man Liu, MD, MBA

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hon-man Liu, MD, MBA

CONTACT

886-2-23123456hmliu@ntu.edu.tw

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chairman

Study Record Dates

First Submitted

January 28, 2014

First Posted

January 30, 2014

Study Start

February 1, 2014

Primary Completion

February 1, 2016

Study Completion

February 1, 2016

Last Updated

January 30, 2014

Record last verified: 2014-01

Locations

TW(1)