NCT02037607

Brief Summary

The purpose of this study is to determine how frequently children undergoing elective neurosurgical procedures develop blood clots in the deep veins of the legs while hospitalized. The information gained from this study will help us determine when children children need to receive therapy to help prevent this type of blood clot from forming.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2012

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

January 14, 2014

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 16, 2014

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2015

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

April 25, 2017

Completed
Last Updated

October 20, 2017

Status Verified

September 1, 2017

Enrollment Period

2.8 years

First QC Date

January 14, 2014

Results QC Date

March 14, 2017

Last Update Submit

September 20, 2017

Conditions

Keywords

Deep vein thrombosisChildrenPediatricAnti-coagulantNeurosurgical proceduresBlood Clot

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With Post-operative Ultrasound Without Evidence of Thromboembolism

    The number of participants with post-operative ultrasound without evidence of thromboembolism

    within 72 hours after surgery

Eligibility Criteria

Age1 Month - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

100 children between the ages of 1 month-12 years having an elective neurosurgical procedure at James Whitcomb Riley Hospital for Children.

You may qualify if:

  • Patients age 1 month-12 years undergoing elective neurosurgical procedures.

You may not qualify if:

  • Patients undergoing outpatient neurosurgical procedures
  • Patients with known DVT
  • Patients with known hypercoagulable state
  • Patients at high risk for DVT (discretion of surgeon in consultation with the hematology service)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

James Whitcomb Riley Hospital for Children

Indianapolis, Indiana, 46202, United States

Location

Related Publications (1)

  • Scherer AG, White IK, Shaikh KA, Smith JL, Ackerman LL, Fulkerson DH. Risk of deep venous thrombosis in elective neurosurgical procedures: a prospective, Doppler ultrasound-based study in children 12 years of age or younger. J Neurosurg Pediatr. 2017 Jul;20(1):71-76. doi: 10.3171/2017.3.PEDS16588. Epub 2017 May 5.

MeSH Terms

Conditions

Venous ThrombosisThrombosis

Condition Hierarchy (Ancestors)

Embolism and ThrombosisVascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Heather Cero, Research Nurse Manager
Organization
Indiana University

Study Officials

  • Daniel H Fulkerson, M.D.

    Indiana University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Neurosurgeon

Study Record Dates

First Submitted

January 14, 2014

First Posted

January 16, 2014

Study Start

September 1, 2012

Primary Completion

July 1, 2015

Study Completion

July 1, 2015

Last Updated

October 20, 2017

Results First Posted

April 25, 2017

Record last verified: 2017-09

Locations