NCT02036203

Brief Summary

This study aims to evaluate the safety and efficacy of the IUB SCu300A spherical copper IUD compared to the standard T shaped copper IUD, the TCu380. Participants will be followed for one year and quality of life measurements will be measured during this period as well.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jan 2014

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 23, 2013

Completed
22 days until next milestone

First Posted

Study publicly available on registry

January 14, 2014

Completed
Same day until next milestone

Study Start

First participant enrolled

January 14, 2014

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 14, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 14, 2014

Completed
Last Updated

July 6, 2018

Status Verified

July 1, 2018

Enrollment Period

Same day

First QC Date

December 23, 2013

Last Update Submit

July 4, 2018

Conditions

Outcome Measures

Primary Outcomes (4)

  • Perforation rate

    Number of subjects with partial or complete perforation through the uterine wall

    During device insertion

  • Device expulsion

    Number of subjects with partially or fully ejected devices

    12 months

  • Efficacy in preventing pregnancy

    Number of women who become pregnant during the trial period.

    12 months

  • Device malposition

    Number of subjects with observed device malposition within the uterine cavity

    12 months

Secondary Outcomes (1)

  • Menorrhagia and dysmenorrhea rates

    12 months

Study Arms (2)

SCu300A IUB

EXPERIMENTAL
Device: SCu300A IUB

TCu380A

ACTIVE COMPARATOR
Device: TCu380A IUD

Interventions

Spherical copper contraceptive

SCu300A IUB

T-shaped copper IUD

TCu380A

Eligibility Criteria

Age25 Years - 42 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • \* Adult females aged 25-42
  • Free and willing to fully comply with treatment process
  • Healthy women seeking LARC
  • Married or in a steady relationship (at least 1 year)
  • Blood hemoglobin \>11.5gr%
  • Signed informed consent form
  • If took COCP at least had one cycle after use of OC

You may not qualify if:

  • Use IUB/IUD as an emergency contraception
  • A previously placed IUD that has not been removed
  • Pregnancy or suspicion of pregnancy
  • Use of other contraception method (condom for either male or female, oral contraceptives, diaphragms, spermicides, hormonal patches, injections or ring, cervical cap)
  • History of pelvic inflammatory disease, recent or remote.
  • Postpartum endometritis or post abortal endometritis in the past 3 month
  • Mucopurulent cervicitis
  • Endometrial thickness more than 12 mm on insertion date
  • Known anemia
  • History of previous IUD complications
  • Dysfunctional uterine bleeding
  • Undiagnosed uterine bleeding
  • Malignancy or suspected malignant disease of female inner or outer genitalia
  • Distortions of the uterine cavity by uterine fibroids or known anatomical abnormalities
  • Known intolerance or allergy to nitinol or copper and/or copper IUDs - Wilson's disease.
  • +7 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Women's Health Center

Netanya, Israel

Location
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 23, 2013

First Posted

January 14, 2014

Study Start

January 14, 2014

Primary Completion

January 14, 2014

Study Completion

January 14, 2014

Last Updated

July 6, 2018

Record last verified: 2018-07

Locations