NCT02031705

Brief Summary

It has been demonstrated that successful cavotricuspid isthmus ablation may be effective in preventing paroxysmal atrial fibrillation. However, the effectiveness of only isthmus ablation on atrial fibrillation itself is unclear.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
366

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2012

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

September 9, 2013

Completed
4 months until next milestone

First Posted

Study publicly available on registry

January 9, 2014

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2019

Completed
Last Updated

April 23, 2024

Status Verified

April 1, 2024

Enrollment Period

6.9 years

First QC Date

September 9, 2013

Last Update Submit

April 21, 2024

Conditions

Keywords

FibrillationCatheter ablation

Outcome Measures

Primary Outcomes (1)

  • Freedom of AF and Af

    1 month, 3 months and 12months after ablation follow up visit and Check the recurrence of atrial fibrillation through EKG,Holter, event recording

    1 year after catheter ablation

Study Arms (2)

cavotricuspid isthmus ablation

ACTIVE COMPARATOR

Isthmus ablation was performed in paroxysmal atrial fibrillation patients.

Procedure: cavotricuspid isthmus ablation

control group

PLACEBO COMPARATOR

Control group was performed no additional cavotricuspid isthmus ablation.

Procedure: control group

Interventions

Isthmus ablation was performed in paroxysmal atrial fibrillation patients.

cavotricuspid isthmus ablation
control groupPROCEDURE

Control group was performed no additional cavotricuspid isthmus ablation.

control group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Scheduled ablation for paroxysmal atrial fibrillation

You may not qualify if:

  • Typical atrial flutter
  • History of artificial tricuspid valve surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul st. mary's hospital

Seoul, South Korea

Location

Related Publications (1)

  • Kim SH, Oh YS, Choi Y, Hwang Y, Kim JY, Kim TS, Kim JH, Jang SW, Lee MY, Joung B, Choi KJ. Long-Term Efficacy of Prophylactic Cavotricuspid Isthmus Ablation during Atrial Fibrillation Ablation in Patients Without Typical Atrial Flutter: a Prospective, Multicentre, Randomized Trial. Korean Circ J. 2021 Jan;51(1):58-64. doi: 10.4070/kcj.2020.0174. Epub 2020 Sep 14.

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • SungHwan Kim, MD

    Seoul St. Mary's Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 9, 2013

First Posted

January 9, 2014

Study Start

July 1, 2012

Primary Completion

June 1, 2019

Study Completion

August 1, 2019

Last Updated

April 23, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share

Locations