Project Healthy Eating in Adults. A Study on the Health Effects of Fish Intake in Overweight Adults (FINS)
Title in Norwegian: Sunn og Frisk. En Studie av Helseeffekter av Fiskeinntak i Overvektige Voksne (FINS)
1 other identifier
interventional
183
1 country
1
Brief Summary
It has previously been observed that increased fish intake improves the metabolic health of overweight and obese adults, and animal protein improved metabolic health of obese rats. In this project the investigators will investigate whether increased intake of fish or meat improves metabolic health in overweight/obese adults aged 20-55 years when replacing processed food. The hypothesis is that increased intake of unprocessed fish or meat will improve metabolic health in adults as measured by glucose tolerance, lipid metabolism and inflammatory markers.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2014
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 17, 2013
CompletedFirst Posted
Study publicly available on registry
January 1, 2014
CompletedStudy Start
First participant enrolled
January 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2019
CompletedApril 30, 2021
April 1, 2021
1.4 years
December 17, 2013
April 27, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Changes in metabolic status (glucose, lipids, inflammation)
The effects of fish intake on glucose homeostasis, lipid metabolism and inflammation will be assessed.
Baseline and end of intervention (12 weeks)
Secondary Outcomes (2)
Changes in plasma concentrations of amino acids and their metabolites
Baseline and end of intervention (12 weeks)
Changes in plasma concentrations of vitamins
Baseline and end of intervention (12 weeks)
Study Arms (3)
Salmon Group
EXPERIMENTALParticipants will eat 150g salmon for dinner, 3 times per week for 12 weeks
Cod Group
EXPERIMENTALParticipants will eat 150g cod for dinner, 3 times per week for 12 weeks
Meat Group
ACTIVE COMPARATORParticipants will eat 150g mixed meat for dinner, 3 times per week for 12 weeks
Interventions
Eligibility Criteria
You may qualify if:
- BMI \> 27
- years
- healthy
You may not qualify if:
- diagnosed diseases such as diabetes, CVD, intestinal diseases, arthritis
- prescription medications affecting the metabolism of glucose, lipids or the immune system
- use of supplements containing long chain n-3 fatty acids
- high intake of fish
- food allergy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Bergen
Bergen, Norway
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Oddrun A Gudbrandsen, PhD
University of Bergen
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Researcher
Study Record Dates
First Submitted
December 17, 2013
First Posted
January 1, 2014
Study Start
January 1, 2014
Primary Completion
June 1, 2015
Study Completion
December 1, 2019
Last Updated
April 30, 2021
Record last verified: 2021-04