NCT02024048

Brief Summary

The purpose of this study is to evaluate choroidal thickness and volume during the third trimester of pregnancy by comparison with a group of age-matched non-pregnant healthy group of women

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2013

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2013

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

December 18, 2013

Completed
13 days until next milestone

First Posted

Study publicly available on registry

December 31, 2013

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

January 28, 2014

Status Verified

January 1, 2014

Enrollment Period

1 month

First QC Date

December 18, 2013

Last Update Submit

January 27, 2014

Conditions

Keywords

PregnancyOCTEnhanced depth imagingChoroid

Outcome Measures

Primary Outcomes (1)

  • Choroidal thickness

    Comparison of choroidal thickness between the pregnant group of women and the age-matched group of control subjects

    3rd trimester of pregnancy (from 28 weeks gestation to delivery)

Secondary Outcomes (1)

  • Change in choroidal thickness

    During the 3rd trimester (from 28 weeks gestation to delivery) and at 6 months post partum

Study Arms (2)

Pregnant

OCT

Other: OCT

Control

OCT

Other: OCT

Interventions

OCTOTHER

Optical coherence tomography in enhanced depth imaging mode

ControlPregnant

Eligibility Criteria

Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy pregnant women in the third trimester of pregnancy

You may qualify if:

  • Pregnant women:
  • uncomplicated pregnancy in the third trimester (from 28 weeks of gestation)
  • For both groups:
  • no systemic or ocular disease
  • absence of systemic medication other than prenatal vitamins
  • no smoking habits
  • emmetropia or a small refractive error (spherical equivalent \<1.5 diopters)

You may not qualify if:

  • any of the above

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho Vila Nova de Gaia

Vila Nova de Gaia, Portugal

Location

Study Officials

  • Renata Rothwell, Dr

    Department of Opthalmolgy, Centro Hospitalar Vila Nova de Gaia/Espinho

    PRINCIPAL INVESTIGATOR
  • Sofia Fonseca, Dr

    Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho

    PRINCIPAL INVESTIGATOR
  • Marisa Oliveira, Dr

    Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho

    PRINCIPAL INVESTIGATOR
  • Lígia Ribeiro, Dr

    Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho

    PRINCIPAL INVESTIGATOR
  • Dália Meira, Dr

    Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

December 18, 2013

First Posted

December 31, 2013

Study Start

December 1, 2013

Primary Completion

January 1, 2014

Study Completion

July 1, 2014

Last Updated

January 28, 2014

Record last verified: 2014-01

Locations