NCT02016794

Brief Summary

Degenerative cervical spine conditions lead to chronic neck and arm pain. Surgical treatment may require anterior decompression and fusion, which usually is established with a cage implant. The Anterior Cervical Interbody Spacer (ACIS) is such a cage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
9

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2014

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 10, 2013

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 20, 2013

Completed
1 month until next milestone

Study Start

First participant enrolled

February 1, 2014

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
1.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

August 13, 2020

Status Verified

August 1, 2020

Enrollment Period

1.9 years

First QC Date

December 10, 2013

Last Update Submit

August 11, 2020

Conditions

Keywords

cervicalinterbodyspacerdegenerativepainneckdecompressionfusionimplant

Outcome Measures

Primary Outcomes (1)

  • Effect of neck pain on everyday life measured by the Neck Disability Index (NDI).

    6 months

Secondary Outcomes (4)

  • Pain

    Baseline; 1-2days; 6 weeks; 6 months

  • Handling details

    Intraoperative

  • Length of Hospital Stay

    Expected average of 5 days

  • Adverse Events

    Intra and post operative

Study Arms (1)

Patients

Patients suffering from degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients undergoing surgery for degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels

You may qualify if:

  • Age 21 years or older
  • Degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels
  • Degenerative cervical disc disease C3 through Th1 or
  • Ruptured and herniated discs C3 through Th1
  • Ability to understand the content of the patient information / informed consent form
  • Willingness and ability to participate in the registry according to the registry plan (RP)
  • Signed and dated IRB / EC-approved written informed consent

You may not qualify if:

  • Spinal tumor
  • Osteoporosis
  • Cervical trauma and instability
  • Any not medically managed severe systemic disease (ie. infection)
  • Recent history of substance abuse (ie, recreational drugs, alcohol) that would preclude reliable assessment
  • Pregnancy or women planning to conceive within the registry period
  • Prisoner
  • Participation in any other medical device or medicinal product clinical investigation or registry within the previous month that could influence the results of the present registry
  • Intraoperative decision to use implants other than the device under investigation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

AZ Klina

Brasschaat, 2020, Belgium

Location

AZ Sint Maarten

Duffel, 2570, Belgium

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
6 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 10, 2013

First Posted

December 20, 2013

Study Start

February 1, 2014

Primary Completion

January 1, 2016

Study Completion

June 1, 2017

Last Updated

August 13, 2020

Record last verified: 2020-08

Locations