Communication Between Hospital and Community Pharmacists: Impact on Drug Management at Discharge
REPHVIM
Impact of Drug Reconciliation at Discharge and Pharmaceutical Communication Between Hospital and Community Pharmacists on Drug Related Problems: Study Protocol for a Cluster Randomized Cross-over Trial
1 other identifier
interventional
1,176
1 country
21
Brief Summary
This study will evaluate the impact of a communication between hospital pharmacist and community pharmacists in addition to drugs reconciliation procedure at discharge. It will be conducted in 21 french public hospitals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2014
Typical duration for not_applicable
21 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 5, 2013
CompletedFirst Posted
Study publicly available on registry
December 10, 2013
CompletedStudy Start
First participant enrolled
January 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2015
CompletedJanuary 24, 2014
January 1, 2014
1.2 years
December 5, 2013
January 23, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
drug related problems (DRP)
The primary outcome is a composite endpoint associated all the problems/dysfunctions that can be observed from the hospital to home during 7 days after discharge. We will be taking in account the occurence of a dysfunction every time that one of the following problems will happen: - first drug problem; the drug taken by the patient has a problem: it is not the right medicine (Name, form, route, dose). The fault may be 1) an error between the processing of transcription at the admission and the discharge, 2) a therapeutic modification related to therapeutic formulary restriction, the home medication is replaced by an another one that may be less adaptated to patient, 3) an error linked to the writing. Second : patient due to patient; the patient doesn't take what was prescribed and / or treatments that he takes are stopped. Third- :presence of a gap in the continuity and duration of therapy: the patient could not have his medication when he's coming at the pharmacy
7 days after patient discharge
Secondary Outcomes (7)
all compounds of the composite primary outcome measure (patient errors, medical error and DRP)
day 7 after discharge
clinical impact of problems
days 7 after discharge
number of non-planned hospitalization
days 35 after discharge
patient satisfaction
day 7 after patient discharge
community pharmacist satisfaction about exchanges with hospital pharmacists
7 days after patient discharge
- +2 more secondary outcomes
Study Arms (2)
intervention
EXPERIMENTALpatients with reconciliation procedure at discharge and included in the exchange process
control
NO INTERVENTIONusual care
Interventions
medication reconciliation at discharge and communication of this intervention to patient's community pharmacist
Eligibility Criteria
You may qualify if:
- patients over 18
- patients attending to the same CP for at least 3 months
- patients speaking french
You may not qualify if:
- patients with a length stay over 21 days (too many therapeutic modifications),
- patients who do not return to home,
- palliative patients and/or expected end of life
- patients that will not give their informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (21)
Centre Hospitalier Alès-Cévennes
Alès, 30100, France
Centre Hospitalier Universitaire
Angers, 49000, France
Centre Hospitalier
Béthune, 62408, France
Centre Hospitalier
Blois, 41000, France
Hopital de la Cavale Blanche
Brest, 29200, France
Hopital ESTAING
Clermont-Ferrand, 63000, France
Hopitaux civils de Colmar
Colmar, 68000, France
Centre Hospitalier Compiègne-Noyon
Compiègne, 60200, France
Centre Hospitalier Universitaire
Grenoble, 38000, France
Hopital Jacques Monod
Le Havre, 76290, France
Centre Hospitalier
Le Mans, 72000, France
CHU Conception
Marseille, 13000, France
Hopital de Mercy Metz-Thionville
Metz, 57085, France
Centre Hospitalier Pierre Bérégovoy
Nevers, 58000, France
Hopital Archet
Nice, 06000, France
Centre Hospitalier
Nîmes, 30000, France
Centre Hospitalier Universitaire
Poitiers, 86000, France
Hopital Inter Armées
Saint-Mandé, 94160, France
Hopital de Hautepierre
Strasbourg, 67000, France
Centre Hospitalier Universitaire
Toulouse, 31000, France
Centre Hospitalier Universitaire
Tours, 37000, France
Related Publications (1)
Pourrat X, Roux C, Bouzige B, Garnier V, Develay A, Allenet B, Fraysse M, Halimi JM, Grassin J, Giraudeau B. Impact of drug reconciliation at discharge and communication between hospital and community pharmacists on drug-related problems: study protocol for a randomized controlled trial. Trials. 2014 Jun 30;15:260. doi: 10.1186/1745-6215-15-260.
PMID: 24981605DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Xavier POURRAT, Pr
Centre Hospitalier Régional Universitaire de Tours
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 5, 2013
First Posted
December 10, 2013
Study Start
January 1, 2014
Primary Completion
April 1, 2015
Study Completion
December 1, 2015
Last Updated
January 24, 2014
Record last verified: 2014-01