NCT02006238

Brief Summary

This is a prospective, randomized, double-blind, crossover study. The purpose of this study is to determine whether Farabloc fabric is effective in alleviation of hot flash symptoms in menopausal women. This study will require all prospective participants to fill out a week of Hot Flash Diary to determine eligibility before beginning the study. All prospective participants will be assessed for hot flash frequency, hot flash distress and hot flash severity according to their perception in the Hot Flash Diary during the experimental period.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 4, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

December 10, 2013

Completed
2 months until next milestone

Study Start

First participant enrolled

February 1, 2014

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2014

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

June 23, 2014

Status Verified

June 1, 2014

Enrollment Period

4 months

First QC Date

December 4, 2013

Last Update Submit

June 19, 2014

Conditions

Keywords

Hot flashFarablocmenopausal women

Outcome Measures

Primary Outcomes (1)

  • Frequency of hot flashes

    The number of hot flashes subjects experienced in the past 24 hours

    in the past 24 hours

Secondary Outcomes (1)

  • Severity of hot flash

    In the past 24 hours

Study Arms (2)

Farabloc

EXPERIMENTAL

The participants will sleep on Farabloc fabric nightly for a week.

Device: FarablocDevice: Nylon Fabric

Nylon Fabric

PLACEBO COMPARATOR

The participants will sleep on Nylon fabric nightly for week.

Device: FarablocDevice: Nylon Fabric

Interventions

FarablocDEVICE

The participants will be randomly received Farabloc (experimental) for one week, followed by a 7 day washout and then crossed over to received the Nylon fabric (placebo) for one week.

FarablocNylon Fabric

The participants will be randomly received Nylon fabric (placebo) for one week, followed by a 7 day washout and then crossed over to receive Farabloc (experimental) for one week.

FarablocNylon Fabric

Eligibility Criteria

Age45 Years - 60 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Women with 12 months amenorrhea
  • Experiencing more than 2 nocturnal hot flashes nightly.

You may not qualify if:

  • Other medical conditions associated with night sweats
  • Currently on medication associated with night sweats
  • Less than 2 nocturnal hot flashes per night
  • Allergies to metals
  • Abnormal mental status
  • MRS scale rating of mild or above
  • Currently on hormone replacement therapy or herbal supplements and cannot safety discontinue these for the duration of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr. Hsiang's office, 510-943 W. Broadway

Vancouver, British Columbia, V5Z 1K3, Canada

RECRUITING

MeSH Terms

Conditions

Hot Flashes

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • York N Hsiang, MB FRCSC

    University of British Columbia, Division of Vascular Surgery and Vancouver General Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

York N Hsiang, MB FRCSC

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 4, 2013

First Posted

December 10, 2013

Study Start

February 1, 2014

Primary Completion

June 1, 2014

Study Completion

December 1, 2014

Last Updated

June 23, 2014

Record last verified: 2014-06

Locations