NCT01997463

Brief Summary

The investigators hypothesize that school-based, direct supervision of daily controller therapy will result in more effective asthma control, as assessed by the Asthma Control Questionnaire than usual care. Additionally, as the result of enhanced asthma control and resulting decrease in health care utilization, school-based, direct supervision of daily controller therapy will result in lower cost per quality-adjusted life year (QALY) gained than usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
442

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Aug 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 22, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 28, 2013

Completed
8 months until next milestone

Study Start

First participant enrolled

August 1, 2014

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
5.8 years until next milestone

Results Posted

Study results publicly available

March 23, 2022

Completed
Last Updated

March 23, 2022

Status Verified

February 1, 2022

Enrollment Period

1.8 years

First QC Date

November 22, 2013

Results QC Date

November 1, 2017

Last Update Submit

February 25, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • The Primary Outcome Will be the Score on the Juniper Asthma Control Questionnaire (ACQ)

    An ACQ score of \> 1.5 means asthma is not well controlled. An ACQ score of \<= 1.5 means asthma is well controlled. Missing ACQ score = number of participants not administered an ACQ

    1 year

Study Arms (2)

Regular Therapy

NO INTERVENTION

Regular Asthma Therapy

Supervised Therapy

EXPERIMENTAL

Supervised asthma therapy in schools

Drug: Supervised asthma therapy in schools

Interventions

Therapy observed daily in school. Asthma education by American Lung Association

Also known as: Inhaled Corticosteroid, Ventolin
Supervised Therapy

Eligibility Criteria

Age5 Years - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • A child with asthma attending a Tucson Unified School District elementary school selected for the study.

You may not qualify if:

  • No asthma.
  • Not attending a Tucson Unified School District elementary school selected for the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Arizona and the Tucson Unified School District

Tucson, Arizona, 85724, United States

Location

Related Publications (1)

  • Gerald JK, Fisher JM, Brown MA, Clemens CJ, Moore MA, Carvajal SC, Bryson D, Stefan N, Billheimer D, Gerald LB. School-supervised use of a once-daily inhaled corticosteroid regimen: A cluster randomized trial. J Allergy Clin Immunol. 2019 Feb;143(2):755-764. doi: 10.1016/j.jaci.2018.06.048. Epub 2018 Aug 14.

MeSH Terms

Interventions

SchoolsAlbuterol

Intervention Hierarchy (Ancestors)

Non-Medical Public and Private FacilitiesEthanolaminesAmino AlcoholsAlcoholsOrganic ChemicalsAminesPhenethylaminesEthylamines

Results Point of Contact

Title
Clara Ehrman
Organization
University of Arizona

Study Officials

  • Lynn B Gerald, Ph.D., MSPH

    University of Arizona, Mel and Enid Zuckerman College of Public Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 22, 2013

First Posted

November 28, 2013

Study Start

August 1, 2014

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

March 23, 2022

Results First Posted

March 23, 2022

Record last verified: 2022-02

Locations