NCT01995630

Brief Summary

The purpose of this study is to evaluate differences in the depth of focus after implantation of a spherical or aspheric IOL in hypermetropic and emmetropic patients. After implantation of a spherical IOL hypermetropic patients may achieve a better depth of focus compared to emmetropic patients due to a larger amount of spherical aberrations.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

November 21, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 26, 2013

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
25 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 26, 2016

Completed
Last Updated

June 28, 2017

Status Verified

June 1, 2017

Enrollment Period

2.6 years

First QC Date

November 21, 2013

Last Update Submit

June 27, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Distance-corrected intermediate visual acuity

    3 month postop

Secondary Outcomes (10)

  • Distance-corrected near visual acuity

    3 month postop

  • Uncorrected distance visual acuity

    3 month postop

  • Corrected distance visual acuity

    3 month postop

  • Uncorrected near visual acuity

    3 month postop

  • Corrected near visual acuity

    3 month postop

  • +5 more secondary outcomes

Study Arms (4)

Hypermetropic, spherical IOL

EXPERIMENTAL

AMO Sensar AR40e

Device: AMO Sensar AR40e

Hypermetropic, aspheric IOL

EXPERIMENTAL

AMO Tecnis ZA9003

Device: AMO Tecnis ZA9003

Emmetropic, spherical IOL

ACTIVE COMPARATOR

AMO Sensar AR40e

Device: AMO Sensar AR40e

Emmetropic, aspheric IOL

ACTIVE COMPARATOR

AMO Tecnis ZA9003

Device: AMO Tecnis ZA9003

Interventions

Emmetropic, aspheric IOLHypermetropic, aspheric IOL
Emmetropic, spherical IOLHypermetropic, spherical IOL

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Cataract
  • Dioptric power of IOL \>22.0 D in hypermetropic patients and 18.0-22.0 D in emmetropic patients, respectively

You may not qualify if:

  • Uveitis, pathology of the retina or the optic nerve
  • Corneal scarring or irregularities
  • Astigmatism \>1.5 D
  • Amblyopia
  • Perioperative complications
  • Postoperative refractive error \>2.0 D of spherical equivalent
  • Postoperative DCVA \<0.8 (ETDRS)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept. of Ophthalmology, Medical University of Graz

Graz, 8036, Austria

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • Navid Ardjomand, MD

    Dept. of Ophthalmology, Medical University of Graz

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Univ.-Doz. Dr. med. univ.

Study Record Dates

First Submitted

November 21, 2013

First Posted

November 26, 2013

Study Start

November 1, 2013

Primary Completion

June 1, 2016

Study Completion

June 26, 2016

Last Updated

June 28, 2017

Record last verified: 2017-06

Locations