Prevalence of Dyschromatopsia in Glaucoma Patients

NCT01994564 | Withdrawn

• 1 other identifier: 356715-1 Dyschromatopsia
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Glaucoma is a progressive disease resulting in loss of retinal nerve cells and their axons (retinal nerve fibers). Retinal nerve fibers are ordered in a special manner when they enter the optic nerve. Hence, damage to the retinal nerve fibers by glaucoma results in visual field defects at certain locations. Furthermore, the retinal nerve fiber layers from different receptors for different colors are ordered in a special manner as well. Thus, it is possible that glaucomatous damage causes color vision dysfunction (dyschromatopsia). At the moment there is disagreement whether dyschromatopsia occurs at early- to mid-stage or only in end-stage glaucoma. By testing color vision in glaucoma patients the prevalence of dyschromatopsia in glaucoma and in different stages of the disease will be investigated.

Conditions

Open Angle Glaucoma

Keywords

OAG

Outcome Measures

Primary Outcomes (1)

• Result from Ishihara Test

  Color vision will be tested once by Ishihara plates. Both eyes will be tested separately.

  Visit 1

Secondary Outcomes (1)

• Glaucoma stage

  Visit 1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with a diagnosis of open-angle glaucoma of the Glaucoma Department at Massachusetts Eye \& Ear Infirmary, Boston, MA 02114, US

You may qualify if:

• diagnosis of open angle glaucoma
• visual acuity \>/= 20/50
• age \>/= 18 (no upper limit)
• male or female gender

You may not qualify if:

• other type of glaucoma
• age \<18
• other retinal disease (e.g. age related macular degeneration)
• other disease affecting the optic nerve or the retinal nerve fibers
• known color blindness

Sponsors & Collaborators

• Massachusetts Eye and Ear Infirmary: lead

Study Sites (1)

Massachusetts Eye & Ear Infirmary

Boston, Massachusetts, 02114, United States

Location

MeSH Terms

Conditions

Glaucoma, Open-Angle

Condition Hierarchy (Ancestors)

Glaucoma; Ocular Hypertension; Eye Diseases

Study Officials

• Douglas J. Rhee, M.D.

  Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA, US

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 19, 2013
• First Posted: November 26, 2013
• Study Start: November 1, 2012
• Primary Completion: December 1, 2013
• Study Completion: January 1, 2014
• Last Updated: November 26, 2013

Record last verified: 2012-07

Locations

US (1)