NCT01984996

Brief Summary

The primary objective of this study is to evaluate patient quality-of-life (QOL) after inguinal hernia repair. "Carolinas Comfort Scale" (CCS) assessments will be held at regular intervals. The secondary objective of the study is to follow short-term and long-term study-related complications/adverse events.

Trial Health

40
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Geographic Reach
3 countries

8 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 4, 2013

Completed
11 days until next milestone

First Posted

Study publicly available on registry

November 15, 2013

Completed
16 days until next milestone

Study Start

First participant enrolled

December 1, 2013

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
Last Updated

June 9, 2016

Status Verified

January 1, 2016

Enrollment Period

4 years

First QC Date

November 4, 2013

Last Update Submit

June 7, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Measure changes from baseline in Carolina Comfort Scale (CCS) scores at specified time intervals

    Measure quality of life for patients undergoing inguinal hernia repair.

    1 week, 3, 6, 9, 12, 18, 24, and 36 months.

Secondary Outcomes (1)

  • Evaluate the 14-day pain and medication log

    14 days

Other Outcomes (1)

  • Study-related complications/adverse events

    3 years

Study Arms (1)

Freedom ProFlor Inguinal Hernia Implant

EXPERIMENTAL
Device: Freedom ProFlor Inguinal Hernia Implant

Interventions

Freedom ProFlor Inguinal Hernia Implant

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Scheduled to undergo routine inguinal hernia repair
  • Competent to give consent
  • Clinically relevant inguinal hernia (classification: NYHUS I, II, IIIa)
  • Defect size at operation is between 5mm and 35mm
  • Diagnosed with unilateral, direct, indirect or mixed inguinal hernia
  • Primary hernia at the operative site
  • Male or female
  • Life expectancy of at least 12 months
  • At least 18 years of age

You may not qualify if:

  • Signs of obvious local or systemic infection
  • Any previous surgery on the hernia operative site
  • Hernia is not in the inguinal area
  • Hernia is not identified as indirect or direct
  • Femoral hernias
  • Known collagen disorder
  • Presenting with unstable angina or NYHA class of IV
  • Known Pregnancy
  • Active drug user
  • Recurrence of a repair by any method
  • Patients with giant inguinoscrotal hernia or abdominal wall defect \>35 mm in diameter - e.g. large direct or combined inguinal hernia type Nyhus IIIb / EHS P L/M 1/2/3
  • Immunosuppression, prednisone\>15 mg/day, active chemotherapy
  • End stage renal disease
  • Abdominal ascites
  • Skin infection in area of surgical field
  • +2 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Metabolic Clinic and Research Center

Los Angeles, California, 90033, United States

Location

Witham Health Services

Lebanon, Indiana, 46052, United States

Location

Our Lady of the Lake Regional Medical Center

Baton Rouge, Louisiana, 70808, United States

Location

New Hannover Regional Medical Center

Wilmington, North Carolina, 28401, United States

Location

Herz Jesu Krankenhaus GmbH

Vienna, A-1030, Austria

Location

Istituto Clinico Sant'Ambrogio

Milan, 20149, Italy

Location

Azienda Policlinico Umberto I

Roma, 00161, Italy

Location

Policlinico Tor Vergata

Roma, 00161, Italy

Location

Study Officials

  • Karl LeBlanc, M.D., M.B.A., F.A.C.S.

    Our Lady of the Lake Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2013

First Posted

November 15, 2013

Study Start

December 1, 2013

Primary Completion

December 1, 2017

Last Updated

June 9, 2016

Record last verified: 2016-01

Locations