Feasibility of Strength Training in Patients Hospitalized Due to COPD

NCT01981200 | Completed DMC

• 1 other identifier: 210977
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD

Conditions

COPD; Muscle Weakness

Keywords

COPD acute exacerbation; Physiotherapy; Resistance training; Muscle strength; Handheld dynamometer

Outcome Measures

Primary Outcomes (1)

• Increase of training load during admission

  Change in training loads measured by the number of kilos lifted using ankle weight cuffs in 3 sets of 10 repetition maximum at the first training day to the number of kilos lifted at the last training day

  The patients will be followed for the duration of hospital stay, an expected average of 6 days

Secondary Outcomes (3)

• Maximal isometric knee extension strength

  The patients will be followed for the duration of hospital stay, an expected average of 6 days

• Sit-to- stand- test

  The patients will be followed for the duration of hospital stay, an expected average of 6 days

• Timed Up and Go (TUG)

  The patients will be followed for the duration of hospital stay, an expected average of 6 days

Study Arms (1)

Resistance training in AECOPD

EXPERIMENTAL

The patients conduct daily training during admission with weight cuff 3 set of 10 rep.

Other: Resistance training in AECOPD

Interventions

Resistance training in AECOPD OTHER

The patients begin training on day 1 of admittance. The training consists of knee extension performed in the sitting position on the bed with a 90 degrees of flexion of the knees. The weight cuffs are tired to the angles with a weight corresponding to 10 RM (the weight lifted 10 times). The weights and exercises are subjected to supervision on daily basis by the physiotherapist. The weight is increased after every set of training if more than 10 rep. can be performed with a given weight. Limitations to exercise is also recorded along with the degree of dyspnoea as assessed by the Borg CR10, possible oxygen supplementation and saturation is recorded before and following exercise.

Also known as: Weight cuffs, Strength training, hospitalization

Resistance training in AECOPD

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Have a primary diagnosis of COPD
• Be admitted to the pulmonary ward due to an exacerbation in COPD
• Provide informed consent to participation in the study
• Be able to maintain an upright position on a chair
• Be able to be guided to training and understand instructions for participating

You may not qualify if:

• Patients suffering from diseases that prevents the use of wrist weights such as
• Deep venous thrombosis (DVT)
• Erysipelas
• Painful edema of the limbs
• Lack of ability to walk, habitually
• Predicted hospital stay of less than four days as predicted by a pulmonary physician
• Patients admitted Friday night or Saturday morning cannot be stared up within 24 hours of admittance

Sponsors & Collaborators

• Frederikssunds Hospital, Denmark: lead
• Copenhagen University Hospital, Hvidovre: collaborator

Study Sites (1)

Nordsjællands Hospital - Frederikssund

Frederikssund, 3600, Denmark

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Muscle Weakness

Interventions

Resistance Training; Hospitalization

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Health Services; Health Care Facilities Workforce and Services

Study Officials

• Linette M Kofod, PT

  Nordsjællands Hospital - Frederikssund

  PRINCIPAL INVESTIGATOR

• Morten T Kristensen, PhD

  Copenhagen University Hospital, Hvidovre

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: October 30, 2013
• First Posted: November 11, 2013
• Study Start: October 1, 2013
• Primary Completion: January 1, 2014
• Study Completion: January 1, 2014
• Last Updated: February 11, 2014

Record last verified: 2014-02

Locations

DK (1)