Attention Bias Modification Treatment for Anxious Youth

NCT01979263 | Terminated

• 1 other identifier: 1207012686R001-IRB
• Study Type: interventional
• Target: 5
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this project is to study the feasibility and efficacy of attention bias modification treatment (ABMT) in a randomized-controlled sample of anxious youth.

Conditions

Generalized Anxiety Disorder; Separation Anxiety Disorder; Social Phobia; Specific Phobia; Obsessive-Compulsive Disorder

Outcome Measures

Primary Outcomes (1)

• Change in clinical severity ratings on Anxiety Disorder Interview Schedule-Child and Parent Version

  after a 6-week intervention and 4-week no-treatment follow-up

Secondary Outcomes (1)

• Variation in genes associated with treatment response

  week 1

Study Arms (2)

Attention Bias Modification

ACTIVE COMPARATOR

Attention Bias Modification computer task

Other: Attention Bias Modification Computer Task

Placebo Computer Task

PLACEBO COMPARATOR

Placebo computer task

Other: Placebo Computer Task

Interventions

Attention Bias Modification Computer Task OTHER

Computer task aimed at actively modifying attention bias

Attention Bias Modification

Placebo Computer Task OTHER

Computer task that does not actively modify attention bias

Placebo Computer Task

Eligibility Criteria

• Age: 7 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Diagnosis on Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual-IV Child and Parent versions of Separation Anxiety Disorder, Social Phobia, Specific Phobia, Obsessive-Compulsive Disorder, or Generalized Anxiety Disorder
• Age 7 to 17

You may not qualify if:

• Posttraumatic stress disorder or primary diagnosis of major depressive disorder
• Seizure disorder
• Current treatment with psychotropic medication
• Multiple chronic learning disabilities and/or conduct problems

Sponsors & Collaborators

• Weill Medical College of Cornell University: lead

Study Sites (2)

Payne Whitney Manhattan Child Division

New York, New York, 10065, United States

Location

New York Presbyterian Hospital--Westchester Division

White Plains, New York, 10605, United States

Location

MeSH Terms

Conditions

Generalized Anxiety Disorder; Anxiety, Separation; Phobia, Social; Phobia, Specific; Obsessive-Compulsive Disorder

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders; Neurodevelopmental Disorders; Phobic Disorders

Study Officials

• Megan H Feltenberger, PhD

  Weill Medical College of Cornell University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 30, 2013
• First Posted: November 8, 2013
• Study Start: October 1, 2013
• Primary Completion: January 17, 2017
• Study Completion: January 17, 2017
• Last Updated: July 30, 2019

Record last verified: 2019-07

Data Sharing

• IPD Sharing: Will share

Locations

US (2)