Trials Sponsors Conditions Drugs Pricing

Conditions

Obstructive Sleep Apnea

Keywords

BiomarkersGenomics

Outcome Measures

Primary Outcomes (1)

Biomarker
Biomarkers related to inflammation, hypoxia, oxidative stress, redox and the central nervous system will be measured
Comparison between 0, 3 and 12 month

Secondary Outcomes (3)

Genomics
Comparison between 0, 3, 12 month
Apnea hypopnea index
Comparision between 0, 3 and 12 month
Exhaled nitric oxide
Comparision at 0, 3 and 12 month

Study Arms (3)

Obstructive sleep apnea patients

Patients with obstructive sleep apnea that has not received CPAP treatment

Matched volunteers with non OSA

Matched volunteers without OSA. Matched in respect to age and BMI

Matched normal controls with normal BMI

Volunteers that are matched according to age but has a normal BMI

Eligibility Criteria

Age18 Years - 75 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

OSA patients will be recruited from an outpatient sleep clinic

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Karolinska University Hospital
Otherlead

Study Sites (1)

Department of Anesthesiology, Surgical Sciences and Intensive Care Medicine, Karolinska University Hospital, Solna

Stockholm, SE-17176, Sweden

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood, serum, plasma

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

Malin Jonsson Fagerlund, MD, PhD
Karolinska University Hospital and Karolinska Institutet
PRINCIPAL INVESTIGATOR

Enrollment

75 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: MD, PhD

Study Record Dates

First Submitted

October 21, 2013

First Posted

November 5, 2013

Study Start

October 1, 2013

Actual (reported)

Evaluation of Potential Biomarkers for Obstructive Sleep Apnea and the Effect of Positive Pressure Treatment

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (3)

Obstructive sleep apnea patients

Matched volunteers with non OSA

Matched normal controls with normal BMI

Eligibility Criteria

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (3)

Obstructive sleep apnea patients

Matched volunteers with non OSA

Matched normal controls with normal BMI

Eligibility Criteria

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations