Adaption of the Skin Sun Sensitivity Scale

NCT01975038 | Completed

• 1 other identifier: STU00086547
• Study Type: observational
• Target: 292
• Locations: 1 country
• Sites: 1

Brief Summary

Determining Fitzpatrick skin phototypes (FST) allows physicians to assess a person's risk of developing sunburn, and thus the need for sun protection to prevent the development of skin cancer. Reflectance spectrophotometry objectively measures the melanin index (MI) and can assist in determining the accuracy of self-reported FST compared with dermatologist-determined FST. At present, we seek to determine the accuracy of an adapted Skin Sun Sensitivity Scale for individuals of all pigmentation varieties (FST I through VI) as compared with spectrophotometric measurements assessing FST. Our principal objective is to correlate the MI under usual conditions by spectrophotometry with the adapted Fitzpatrick SPT as determined by the patients' responses to the adapted questionnaire.

Conditions

Skin Diseases

Keywords

Melanin Index; Fitzpatrick Skin Phototype; Spectrophotometry; Skin Diseases

Outcome Measures

Primary Outcomes (1)

• Melanin Index by Spectrophotometry

  Spectrophotometer measurement is the wavelength of the reflected light measured in nm. It represents the area under the curve for the all wavelengths of light, thus a reading will be expressed as (192 ±30, mean ± SD).

  At baseline

Secondary Outcomes (3)

• Participant Self-Report of Fitzpatrick Skin Type

  At baseline

• Assessment of Ease of Freckling as a Child and Ethnicity

  At baseline

• Assessment of Fitzpatrick Skin Type using the Adapted Skin Phototype Measure

  At baseline

Study Arms (1)

A convenience sample

The characteristics of the sample will be monitored to assure that each category of skin type (I- VI) is accrued in sufficient size to support analysis. In addition, the sample will have equal representation from 4 ethnic groups within each skin type category: African American, Asian, Hispanic, or non-Hispanic White. Participants will self-identify as being Asian, Black, Hispanic Black, Hispanic White, or non-Hispanic White.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A convenience sample of approximately 200 Northwestern University students, employees (faculty and staff), patients attending the dermatology clinic, and attendees of Northwestern University dermatology-related events will be selected for measurement of the melanin index with the Mexameter MX18. The characteristics of the sample will be monitored to assure that each category of skin type (I- VI) is accrued in sufficient size to support analysis. In addition, the sample will have equal representation from 4 ethnic groups within each skin type category: African American, Asian, Hispanic, or non-Hispanic White. Participants will self-identify as being Asian, Black, Hispanic Black, Hispanic White, or non-Hispanic White.

You may qualify if:

• Are at least 18 years old
• Are fluent in English
• Are able to complete the study procedures including answering questionnaires
• Are willing to have spectrophotometry readings taken of right upper inner arm

You may not qualify if:

• Used self-tanning products or tan accelerators on the right upper inner arm in the 4 weeks prior to enrollment

Sponsors & Collaborators

• Northwestern University: lead

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

Location

Related Publications (22)

• Chan JL, Ehrlich A, Lawrence RC, Moshell AN, Turner ML, Kimball AB. Assessing the role of race in quantitative measures of skin pigmentation and clinical assessments of photosensitivity. J Am Acad Dermatol. 2005 Apr;52(4):609-15. doi: 10.1016/j.jaad.2004.03.051.

  PMID: 15793510 BACKGROUND

• Chung JH, Koh WS, Youn JI. Relevance of skin phototyping to a Korean population. Clin Exp Dermatol. 1994 Nov;19(6):476-8. doi: 10.1111/j.1365-2230.1994.tb01250.x.

  PMID: 7889667 BACKGROUND

• Dawson JB, Barker DJ, Ellis DJ, Grassam E, Cotterill JA, Fisher GW, Feather JW. A theoretical and experimental study of light absorption and scattering by in vivo skin. Phys Med Biol. 1980 Jul;25(4):695-709. doi: 10.1088/0031-9155/25/4/008.

  PMID: 7454759 BACKGROUND

• Diffey BL, Oliver RJ, Farr PM. A portable instrument for quantifying erythema induced by ultraviolet radiation. Br J Dermatol. 1984 Dec;111(6):663-72. doi: 10.1111/j.1365-2133.1984.tb14149.x.

  PMID: 6508999 BACKGROUND

• Eilers S, Bach DQ, Gaber R, Blatt H, Guevara Y, Nitsche K, Kundu RV, Robinson JK. Accuracy of self-report in assessing Fitzpatrick skin phototypes I through VI. JAMA Dermatol. 2013 Nov;149(11):1289-94. doi: 10.1001/jamadermatol.2013.6101.

  PMID: 24048361 BACKGROUND

• Feather JW, Ellis DJ, Leslie G. A portable reflectometer for the rapid quantification of cutaneous haemoglobin and melanin. Phys Med Biol. 1988 Jun;33(6):711-22. doi: 10.1088/0031-9155/33/6/005.

  PMID: 3406055 BACKGROUND

• Fitzpatrick TB: Soleil et peau. J Med Esthet 1975, 2:33-34

  BACKGROUND

• Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol. 1988 Jun;124(6):869-71. doi: 10.1001/archderm.124.6.869. No abstract available.

  PMID: 3377516 BACKGROUND

• Kim M, Boone SL, West DP, Rademaker AW, Liu D, Kundu RV. Perception of skin cancer risk by those with ethnic skin. Arch Dermatol. 2009 Feb;145(2):207-8. doi: 10.1001/archdermatol.2008.566. No abstract available.

  PMID: 19221276 BACKGROUND

• Lee JH, Kim TY. Relationship between constitutive skin color and ultraviolet light sensitivity in Koreans. Photodermatol Photoimmunol Photomed. 1999 Dec;15(6):231-5. doi: 10.1111/j.1600-0781.1999.tb00095.x.

  PMID: 10599973 BACKGROUND

• Matts PJ, Dykes PJ, Marks R. The distribution of melanin in skin determined in vivo. Br J Dermatol. 2007 Apr;156(4):620-8. doi: 10.1111/j.1365-2133.2006.07706.x.

  PMID: 17493065 BACKGROUND

• Melski JW, Tanenbaum L, Parrish JA, Fitzpatrick TB, Bleich HL. Oral methoxsalen photochemotherapy for the treatment of psoriasis: a cooperative clinical trial. J Invest Dermatol. 1977 Jun;68(6):328-35. doi: 10.1111/1523-1747.ep12496022.

  PMID: 864273 BACKGROUND

• MONASH S. Skin color. A correlation of reflectance measurement and clinical appearance. Arch Dermatol. 1961 Oct;84:654-9. doi: 10.1001/archderm.1961.01580160118023. No abstract available.

  PMID: 14475328 BACKGROUND

• National Institutes of Health. Strategic Research Plan to Reduce and Ultimately Eliminate Health Disparities Volume 1. Years 2002-2006 U.S. Department of Health and Human Services 2002.

  BACKGROUND

• Park SB, Suh DH, Youn JI. Reliability of self-assessment in determining skin phototype for Korean brown skin. Photodermatol Photoimmunol Photomed. 1998 Oct-Dec;14(5-6):160-3. doi: 10.1111/j.1600-0781.1998.tb00035.x.

  PMID: 9826886 BACKGROUND

• Pershing LK, Tirumala VP, Nelson JL, Corlett JL, Lin AG, Meyer LJ, Leachman SA. Reflectance spectrophotometer: the dermatologists' sphygmomanometer for skin phototyping? J Invest Dermatol. 2008 Jul;128(7):1633-40. doi: 10.1038/sj.jid.5701238. Epub 2008 Jan 17.

  PMID: 18200057 BACKGROUND

• Robinson JK, Joshi KM, Ortiz S, Kundu RV. Melanoma knowledge, perception, and awareness in ethnic minorities in Chicago: recommendations regarding education. Psychooncology. 2011 Mar;20(3):313-20. doi: 10.1002/pon.1736.

  PMID: 20878831 BACKGROUND

• Rubegni P, Cevenini G, Flori ML, Fimiani M, Stanghellini E, Molinu A, Barbini P, Andreassi L. Relationship between skin color and sun exposure history: a statistical classification approach. Photochem Photobiol. 1997 Feb;65(2):347-51. doi: 10.1111/j.1751-1097.1997.tb08569.x.

  PMID: 9066310 BACKGROUND

• Shono S, Imura M, Ota M, Ono S, Toda K. The relationship of skin color, UVB-induced erythema, and melanogenesis. J Invest Dermatol. 1985 Apr;84(4):265-7. doi: 10.1111/1523-1747.ep12265342.

  PMID: 3981038 BACKGROUND

• Stanford DG, Georgouras KE, Sullivan EA, Greenoak GE. Skin phototyping in Asian Australians. Australas J Dermatol. 1996 May;37 Suppl 1:S36-8. doi: 10.1111/j.1440-0960.1996.tb01078.x.

  PMID: 8713010 BACKGROUND

• Stern RS, Momtaz K. Skin typing for assessment of skin cancer risk and acute response to UV-B and oral methoxsalen photochemotherapy. Arch Dermatol. 1984 Jul;120(7):869-73.

  PMID: 6732259 BACKGROUND

• Takiwaki H, Shirai S, Kanno Y, Watanabe Y, Arase S. Quantification of erythema and pigmentation using a videomicroscope and a computer. Br J Dermatol. 1994 Jul;131(1):85-92. doi: 10.1111/j.1365-2133.1994.tb08462.x.

  PMID: 8043425 BACKGROUND

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

• Dennis P West, PhD

  Northwestern University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Professor of Dermatology (MD)

Study Record Dates

• First Submitted: October 28, 2013
• First Posted: November 4, 2013
• Study Start: October 1, 2013
• Primary Completion: July 1, 2014
• Study Completion: July 1, 2014
• Last Updated: August 1, 2014

Record last verified: 2014-07

Locations

US (1)