Stroke's Gait Pattern Modifications of Induced by Repeated BTI

NCT01973023 | Completed

• 1 other identifier: 1687472
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic stroke patients exhibit gait pattern alterations which are mainly due to spasticity and treated with repetitive multifocal botulinum toxin injection(BTI). Several studies demonstrated that single BTI-session in a single muscle of paretic lower limb(LL) improved kinematic gait parameters(GP) but surprisingly none of them assessed the effects of repetitive multifocal BTI on patient's gait pattern and their duration. The aim was to evaluate the impact of repetitive multifocal BTI-sessions on GP of chronic stroke patients. To that end, gait of patients has been compared using 3D-gait analysis after at least 2 consecutive BTI sessions.

Conditions

Effect of Repeated Botulinum Toxin Injection on Gait Pattern in Stroke Patients

Keywords

botulinum toxin injection; stroke; 3D motion analysis; gait pattern

Outcome Measures

Primary Outcomes (1)

• kinematics gait parameters

  peak knee flexion in swing phase(°)

  3h

Secondary Outcomes (1)

• spatiotemporal gait parmeters

  3h

Study Arms (1)

Chronic spastic stroke patients

Chronic spastic stroke patients treated regularly with botulinum toxin injection in lower limb muscles

Other: Motion analysis

Interventions

Motion analysis OTHER

Motion analysis was used to assess the modifications of gait pattern in chronic spastic stroke patients regularly treated with botulinum toxin injection

Chronic spastic stroke patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

STROKE PATIENTS

You may qualify if:

• \>18 years
• a single hemispheric cerebral vascular lesion more than 6 months previously
• able to walk 10 meters without any assistance
• having benefited of at least 2 consecutive BTI sessions, second 3D gait analysis performed at least 3 months after the last BTI.

You may not qualify if:

• patient's refusal to participate to the study
• Inability to read the selected text
• Inability to cooperate
• No affiliation to social security

Sponsors & Collaborators

• Centre d'Investigation Clinique et Technologique 805: lead

Study Sites (1)

Hopital Raymond Poincare

Garches, Garches, 92380, France

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• ROCHE Nicolas, MDPHD

  HOPITAL RAYMOND POINCARE-GARCHES

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MDPHD

Study Record Dates

• First Submitted: October 9, 2013
• First Posted: October 31, 2013
• Study Start: July 1, 2013
• Primary Completion: October 1, 2013
• Study Completion: January 1, 2014
• Last Updated: March 2, 2016

Record last verified: 2014-03

Locations

FR (1)