Assessment of Physical Performance After Oral Supplementation of Magnesium in a Sample of Old Women in Good Health
Magnesium
1 other identifier
interventional
100
1 country
1
Brief Summary
Magnesium deficiency is associated also in the elderly with low physical performance; nevertheless trials about the effect of supplementation of magnesium on physical performance are not available in old people. The aim of our study is to investigate whether 12-weeks of oral magnesium supplementation improves physical performance in healthy elderly women
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2012
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2013
CompletedFirst Submitted
Initial submission to the registry
October 23, 2013
CompletedFirst Posted
Study publicly available on registry
October 29, 2013
CompletedOctober 29, 2013
October 1, 2013
1.2 years
October 23, 2013
October 23, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Changes in short physical performance battery (SPPB)
Baseline and after 12 weeks
Secondary Outcomes (1)
Changes in appendicular skeletal mass (ASMMI)
Baseline and after 12 weeks
Study Arms (2)
Mg oxide
EXPERIMENTALParticipants were supplemented for 12-weeks with 300 mg of daily oral magnesium oxide.
Controls
NO INTERVENTIONThe control group was educated by a trained dietician to follow a healthy diet.
Interventions
Eligibility Criteria
You may qualify if:
- People over 65 years, not residents in nursing home, in good health
You may not qualify if:
- previous supplementation of calcium, potassium or magnesium
- use of pump proton inhibitors or digitalis
- important co-mordidities such renal failure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Geriatrics Division, Department of Medicine
Padua, Padova, 35128, Italy
Related Publications (2)
Dominguez LJ, Barbagallo M, Lauretani F, Bandinelli S, Bos A, Corsi AM, Simonsick EM, Ferrucci L. Magnesium and muscle performance in older persons: the InCHIANTI study. Am J Clin Nutr. 2006 Aug;84(2):419-26. doi: 10.1093/ajcn/84.1.419.
PMID: 16895893BACKGROUNDVeronese N, Berton L, Carraro S, Bolzetta F, De Rui M, Perissinotto E, Toffanello ED, Bano G, Pizzato S, Miotto F, Coin A, Manzato E, Sergi G. Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomized controlled trial. Am J Clin Nutr. 2014 Sep;100(3):974-81. doi: 10.3945/ajcn.113.080168. Epub 2014 Jul 9.
PMID: 25008857DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Medical Doctor
Study Record Dates
First Submitted
October 23, 2013
First Posted
October 29, 2013
Study Start
January 1, 2012
Primary Completion
March 1, 2013
Study Completion
March 1, 2013
Last Updated
October 29, 2013
Record last verified: 2013-10