Youth Drug Abuse Prevention in Kazakhstan

NCT01969305 | Completed

• 2 other identifiers: IRB13-0841R34DA033201
• Study Type: interventional
• Target: 181
• Locations: 1 country
• Sites: 1

Brief Summary

This pilot study will adapt and test the feasibility and estimate the effect size parameters of Kazakhstani Family Together (KFT), a family-based multi-media intervention designed to reduce sexual and drug-related risks for HIV infection among at-risk 14-17 year old females and males living in communities highly affected by heroin trade and use in Almaty, Kazakhstan.

Conditions

Drug Use

Keywords

Kazakhstan; Central Asia; HIV prevention; Adolescents; Sexual risk behaviors; Drug abuse prevention; Multi-media intervention; Drug use

Outcome Measures

Primary Outcomes (1)

• Change in onset and 30-day alcohol and drug use from baseline to 6 months

  Measures will ask youth to report the frequency and quantity of alcohol and drug use in the past 30 days (number of alcoholic drinks, puffs of marijuana, or initiation of injection drug use). Substance use includes specific probes, including street names for alcohol, marijuana, ecstasy, cocaine, injecting drug use, heroin, inhalants, hallucinogens, and other drugs as appropriate to the context.

  Up to 6-months

Secondary Outcomes (1)

• Change in onset and sexual risk behaviors from baseline to 6 months

  Up to 6-months

Study Arms (2)

Kazakhstani Family Together (KFT)

EXPERIMENTAL

Usual Care Plus KFT: Family-based multi-media HIV and drug abuse prevention intervention

Behavioral: Kazakhstani Family Together

Health education curriculum

EXPERIMENTAL

Usual Care Alone: Health education curriculum on HIV and drug use prevention

Behavioral: Usual Care Alone

Interventions

Kazakhstani Family Together BEHAVIORAL

Adolescent-caregiver pairs will receive three 45-minute interactive multi-media sessions with avatars customized to participants' gender that will focus on risk reduction self-efficacy, resistance to peer pressure, decision-making skills and caregiver-adolescent communication, support and monitoring to strengthen youth's relationships with caregivers and reduce youth's risks of drug use and sexual risk behaviors. Through the multimedia tool, participants will confront a series of sexual risks and substance use related situations and will practice their listening, empathy, assertiveness, refusal, and other interpersonal skills. Each caregiver-youth pair will work jointly and engage in discussions, exercises, and behavioral rehearsal as directed by the program.

Kazakhstani Family Together (KFT)

Usual Care Alone BEHAVIORAL

Adolescents from both study arms will receive the usual care, a health education program about how to prevent drug use and HIV/STIs (sexually transmitted infections). The health education curriculum is delivered in a group format by trained peer educators and outreach workers. The curriculum consists of three 45-minute sessions that include lectures and interactive quizzes about drugs and HIV. These three sessions include information on the following topics: 1. Facts and Myth about HIV. HIV/STIs modes of transmission; 2. Prevention of HIV. Abstinence and Safe Sex. Attitudes and values about sexuality, sexual risk behaviors, and condom use; 3. Knowledge, attitudes and beliefs about drinking and drug use. Risks and consequences of drug use.

Health education curriculum

Eligibility Criteria

• Age: 14 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Youth are between the ages of 14-17.
• Youth exhibits one of the following risk factors: substance-using peers or friends, parental history of drug use, parental history of alcohol problems, parental criminal history, adolescent's history of drug use, running away from home, school drop-out or history of sexual activity.
• You and caregiver are able to speak and read Russian.
• Both youth and caregiver (parent or other caregiving adult family member) can commit to study participation.
• Youth and caregiver do not plan to move in the next 6 months.

You may not qualify if:

• Youth are under the age of 14 or over the age of 17.
• Youth does not exhibit one of the aforementioned risk factors.
• Youth and caregiver do not speak and read Russian.
• Youth and caregiver are unable to commit to study participation.
• Youth or caregiver has plans to move within the next 6 months.
• Youth or caregiver has a cognitive impairment.

Sponsors & Collaborators

• University of Chicago: lead
• National Institute on Drug Abuse (NIDA): collaborator
• Columbia University: collaborator

Study Sites (1)

Columbia University Global Heath Research Center of Central Asia

Almaty, Kazakhstan

Location

Related Publications (2)

• Ismayilova L, Terlikbayeva A. Building Competencies to Prevent Youth Substance Use in Kazakhstan: Mixed Methods Findings From a Pilot Family-Focused Multimedia Trial. J Adolesc Health. 2018 Sep;63(3):301-312. doi: 10.1016/j.jadohealth.2018.04.005. Epub 2018 Jul 10.

  PMID: 30006027 RESULT

• Ismayilova L, Terlikbayeva A, Rozental Y. Computerized intervention to prevent drug use among at-risk adolescents in Central Asia: Preliminary family-level findings from a pilot mixed methods trial. Int J Drug Policy. 2019 Jun;68:75-85. doi: 10.1016/j.drugpo.2019.03.022. Epub 2019 Apr 16.

  PMID: 31003194 RESULT

Study Officials

• Leyla Ismayilova, PhD

  University of Chicago School of Social Service Administration

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 6, 2013
• First Posted: October 25, 2013
• Study Start: January 1, 2014
• Primary Completion: September 1, 2015
• Study Completion: May 1, 2016
• Last Updated: May 22, 2019

Record last verified: 2018-09

Locations

KA (1)