NCT01963507

Brief Summary

The study aimed to evaluate the chronic effects of resistance training on blood pressure and biochemical exams in hypertensive elderlies and the influence of the polymorphism of the angiotensin converting enzyme in these response.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
136

participants targeted

Target at P50-P75 for not_applicable hypertension

Timeline
Completed

Started Apr 2010

Typical duration for not_applicable hypertension

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2010

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2013

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

October 9, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 16, 2013

Completed
Last Updated

October 16, 2013

Status Verified

October 1, 2013

Enrollment Period

3 years

First QC Date

October 9, 2013

Last Update Submit

October 11, 2013

Conditions

Hypertension

Outcome Measures

Primary Outcomes (1)

  • Blood Pressure

    Blood pressure was measured by Ambulatorial Monitoring Blood Pressure before and after 16 weeks of intervention.

    16 weeks

Secondary Outcomes (13)

  • HDL-cholesterol

    16 weeks

  • Total Cholesterol

    16 weeks

  • Glycemia

    16 weeks

  • Triacylglycerol

    16 weeks

  • PAI-1

    16 weeks

  • +8 more secondary outcomes

Study Arms (2)

Resistance training

EXPERIMENTAL

Resistance training performed three times at week for 16 weeks, in 8 exercises for the main muscles, the protocol of 3 sets of 10 repetitions with intensity of 50% of 1 maximum repetition (MR).

Behavioral: Resistance training

Control

NO INTERVENTION

Interventions

Resistance trainingBEHAVIORAL

Resistance training performed three times at week for 16 weeks, in 8 exercises for the main muscles, the protocol of 3 sets of 10 repetitions with intensity of 50% of 1 maximum repetition (MR).

Resistance training

Eligibility Criteria

Age60 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hypertensives
  • Age 60 to 85 years
  • Nonactive

You may not qualify if:

  • Orthopedic problems or other problem that prevented the exercises
  • Change in drug treatment during protocol
  • Absence in more than 25% of the exercise sessions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UNIMED

Santos, São Paulo, Brazil

Location

MeSH Terms

Conditions

Hypertension

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD

Study Record Dates

First Submitted

October 9, 2013

First Posted

October 16, 2013

Study Start

April 1, 2010

Primary Completion

April 1, 2013

Study Completion

April 1, 2013

Last Updated

October 16, 2013

Record last verified: 2013-10

Locations

BR(1)