NCT01959581

Brief Summary

The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk group through the use of a movement assisting device.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2014

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 8, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 10, 2013

Completed
7 months until next milestone

Study Start

First participant enrolled

May 1, 2014

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
9 months until next milestone

Results Posted

Study results publicly available

July 6, 2017

Completed
Last Updated

July 6, 2017

Status Verified

June 1, 2017

Enrollment Period

2.4 years

First QC Date

October 8, 2013

Results QC Date

February 6, 2017

Last Update Submit

June 6, 2017

Conditions

Keywords

Wilmington Robotic ExoskeletonReachingUpper extremity functionPreterm InfantsBrain injuryPediatricsEarly InterventionArthrogryposis

Outcome Measures

Primary Outcomes (1)

  • Change in Time Contacting Objects

    Percent of the assessment time participants are able to contact objects across different locations. Change within each session with versus without the exoskeleton donned. Slope of change across time in the intervention phase relative to in the baseline phase.

    7 months

Study Arms (1)

Movement enhancing device

OTHER

Guided play while wearing a movement assisting device

Device: Movement Enhancing Device

Interventions

Naturalistic play activities using the hands while wearing the movement enhancing device.

Also known as: WREX (Wilmington Robotic Exoskeleton)
Movement enhancing device

Eligibility Criteria

Age1 Month - 6 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Infants will be invited to participate if they are between 1 month and 6 years and:
  • Were born \< 36 weeks of gestational age with periventricular leukomalacia or grade III or IV intraventricular hemorrhage
  • Were born \> 36 weeks of gestational age with encephalopathy related to perinatal asphyxia
  • Have the diagnosis of neonatal stroke or intracranial hemorrhage
  • Have brachial plexus palsy
  • Have arthrogryposis multiplex congenital
  • Have Down syndrome
  • Have congenital hypotonia

You may not qualify if:

  • blindness or severe sensory motor impairments that would prohibit the child from completing the study assessment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Christiana Care Health Services

Newark, Delaware, 19713, United States

Location

University of Delaware

Newark, Delaware, 19716, United States

Location

Nemours Foundation

Wilmington, Delaware, 19803, United States

Location

MeSH Terms

Conditions

Brain InjuriesArthrogryposis

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemWounds and InjuriesJoint DiseasesMusculoskeletal DiseasesMuscular DiseasesMusculoskeletal AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Results Point of Contact

Title
Michele A. Lobo
Organization
University of Delaware

Study Officials

  • Michele A Lobo, PT, PhD

    University of Delaware

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
Coders are blind to which study phase participants are in
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 8, 2013

First Posted

October 10, 2013

Study Start

May 1, 2014

Primary Completion

October 1, 2016

Study Completion

October 1, 2016

Last Updated

July 6, 2017

Results First Posted

July 6, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations