Venous Thromboembolism Prophylaxis in a Tertiary UAE Hospital: Comparison of Clinical Practice Guidelines.

NCT01958203 | Completed

• 1 other identifier: 122012-11
• Study Type: observational
• Target: 386
• Locations: 0 countries
• Sites: N/A

Brief Summary

Study Title:Assessment of Adherence to Guidelines for Thromboprophylaxis in a Tertiary United Arab Emirates (UAE) hospital Study Site: Al Qassimi Hospital, United Arab Emirates Study Objectives: The primary objective of this study is assessment of appropriateness of VTE prophylaxis administered to critically ill and surgical patients for whom pharmacologic treatment is indicated according to the American College of Chest Physicians (ACCP) 2012 guidelines. The secondary objective is to: 1.Identify some causes of inadequate VTE prophylaxis in different patient populations, such as prescribing problems and errors at the level of administration. Study Design: Cross sectional retrospective observational study Sample size: Approximately 400 Study Population: Inclusion criteria Patients who meet the following criteria will be included:

1. 1.Patients aged 18 and above.
2. 2.Patients admitted to any of the critical care units, or the general or orthopaedic surgical wards.
3. 3.Patients who have been in hospital more than 24 hours.
4. 4.Caprini score \> 1 (see procedure)
5. 5.Patients who have been admitted to a critical care unit and transferred out to a non surgical unit within 24 hours of admission.
6. 6.Patients receiving oral anticoagulant therapy for indications other than VTE prophylaxis or treatment, such as atrial fibrillation and prosthetic heart valves.

Conditions

Venous Thromboembolism

Outcome Measures

Primary Outcomes (1)

• Number of patients receiving inappropriate or inadequate VTE prophylaxis

  Case Report Form Analysis Form

  2 weeks

Secondary Outcomes (1)

• Number of patients receiving inadequate VTE prophylaxis due to medication errors, missed doses etc.

  2 weeks

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The targe sample is paients in critical care wards and orthopaedic surgery patients. All patients will be screened at discharge. Those who fulfill the inclusion/exclusion criteria will go on to have a thromboembolism risk assessment using the CapriniRisk Assessment Model. Those who have a score \> 1 will be included for assessment of their VTE prophylaxis (from medical records). Approximately 60 patients are admitted into critical care units and 40 general and orthopaedic surgical patients are admitted to the surgical wards per month, giving a total sample of around 400 patients.

You may qualify if:

• Patients aged 18 and above.
• Patients admitted to any of the critical care units, or the general or orthopaedic surgical wards.
• Patients who have been in hospital more than 24 hours.
• Caprini score \> 1 (see procedure)

You may not qualify if:

• Patients who have been admitted to a critical care unit and transferred out to a non surgical unit within 24 hours of admission.
• Patients receiving oral anticoagulant therapy for indications other than VTE prophylaxis or treatment, such as atrial fibrillation and prosthetic heart valves.

Sponsors & Collaborators

• Ministry of Health, United Arab Emirates: lead

MeSH Terms

Conditions

Venous Thromboembolism

Condition Hierarchy (Ancestors)

Thromboembolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Ghada Al Tajir, Ph.D

  Clinical Research Centre, Ministry of Health, United Arab Emirates

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Clinical Research Centre

Study Record Dates

• First Submitted: September 29, 2013
• First Posted: October 9, 2013
• Study Start: January 1, 2013
• Primary Completion: August 1, 2013
• Study Completion: September 1, 2013
• Last Updated: October 9, 2013

Record last verified: 2013-10