NCT01953302

Brief Summary

Ventral hernias, primary and recurrent, are major surgical challenge. We aim to investigate efficacy of modified technique of ventral hernias repair: an "open intraperitoneal mesh" technique.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
124

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2010

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

September 21, 2013

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 30, 2013

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2014

Completed
10 years until next milestone

Results Posted

Study results publicly available

April 12, 2024

Completed
Last Updated

April 12, 2024

Status Verified

April 1, 2017

Enrollment Period

4 years

First QC Date

September 21, 2013

Results QC Date

August 31, 2023

Last Update Submit

April 6, 2024

Conditions

Keywords

ventral herniainfectionhematomaseromarecurrencemesh technique

Outcome Measures

Primary Outcomes (1)

  • Number of Early Postoperative Complications (Wound Infections, Seroma, Hematoma)

    we counted number of patinetns with wound infection, seroma, hematoma that occured in the early postoperative time

    four weeks after the surgery

Secondary Outcomes (1)

  • Number of Patients With Postoperative Hernia Recurrence

    up to 36 months after the surgery

Study Arms (1)

modified "open mesh technique"

EXPERIMENTAL

We performed an "open" intraperitoneal mesh technique in all patients: we placed surgical mesh of appropriate size intraperitoneally with transfascial fixation and drainage.

Procedure: modified "open mesh technique"

Interventions

We positioned mesh intraperitoneally so it can provide adequate mechanical support to the weakened abdominal wall. We also preserved hernia sack to conceal the mesh.

Also known as: Proceed Surgical Mesh, VycrilTM,2-0 resorbing sutures
modified "open mesh technique"

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients aged 18 years or older
  • American Society of Anesthesiologists physical status I, II, III

You may not qualify if:

  • refusal of the patients to give informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Varazdin General Hospital

Varaždin, HR-42000, Croatia

Location

Related Publications (1)

  • Pajtak A, Stare R, Biskup I, Lukic A, Skorjanec S, Hrzenjak K. A modified open intraperitoneal mesh (Garestin) technique for incisional ventral hernia repair. Asian J Surg. 2017 Jul;40(4):278-284. doi: 10.1016/j.asjsur.2016.02.001. Epub 2016 May 18.

MeSH Terms

Conditions

Hernia, VentralInfectionsHematomaSeromaRecurrence

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsHemorrhagePathologic ProcessesInflammationDisease Attributes

Results Point of Contact

Title
Alen Pajtak
Organization
Varazdin General Hospital

Study Officials

  • Ranko Stare, MD, PhD

    Varazdin General Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 21, 2013

First Posted

September 30, 2013

Study Start

May 1, 2010

Primary Completion

May 1, 2014

Study Completion

May 1, 2014

Last Updated

April 12, 2024

Results First Posted

April 12, 2024

Record last verified: 2017-04

Locations