NCT01937936

Brief Summary

Family caregivers are vulnerable to health problems because of the stress and demands of their role as a caregiver. With the growing incidence of heart failure (HF) and the anticipated growth in the aging population, the number of HF caregivers is expected to rise. This study will pilot test a cognitive behavioral intervention designed to reduce stress among HF caregivers, which will ultimately contribute to promoting health and quality of life among HF caregivers and their loved ones with HF.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2013

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

September 4, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 10, 2013

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

October 27, 2016

Status Verified

October 1, 2016

Enrollment Period

1.7 years

First QC Date

September 4, 2013

Last Update Submit

October 26, 2016

Conditions

Keywords

caregiver stressdepressionquality of lifecognitive behavioral therapy

Outcome Measures

Primary Outcomes (1)

  • Salivary cortisol

    8 weeks

Secondary Outcomes (4)

  • Perceived stress

    8 weeks and 6 months

  • Depressive symptoms

    8 weeks and 6 months

  • Health-related quality of life

    8 weeks and 6 months

  • Health care usage

    6 months

Study Arms (2)

CBT

EXPERIMENTAL

Cognitive Behavioral Therapy (CBT)

Behavioral: Cognitive Behavioral Therapy (CBT)

Education

ACTIVE COMPARATOR

Health Education

Behavioral: Health Education

Interventions

Family caregivers in the CBT group will receive 8 1-hour weekly Cognitive Behavioral Therapy (CBT) sessions, which will take place in their home.

Also known as: Cognitive Therapy, Cognitive Behavioral Intervention, CBT
CBT

Family caregivers in the Education group will receive 8 1-hour weekly sessions of general health education on selected topics, which will take place in their home.

Education

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • Having primary or secondary diagnosis of HF (NYHA class II-IV)
  • Having a family member or friend providing care for them at home
  • Being able to communicate in English

You may not qualify if:

  • Being on the transplant list
  • Having terminal illness (e.g., terminal cancer)
  • years or older
  • Having the primary responsibility for the care of the patient for at least 6 months
  • Living in the greater Los Angeles area
  • Being able to communicate in English
  • Being a paid caregiver (an individual who is hired to provide care for the patient)
  • Having terminal illness (e.g., terminal cancer) or a serious medical condition that requires ongoing medical care (e.g., cancer requiring ongoing chemotherapy or radiation therapy)
  • Having a history of major psychiatric illness (i.e., schizophrenia, bipolar disorder, and/or any personality disorder)
  • Diagnosed with Cushing's or Addison's disease
  • Taking medication that could influence cortisol levels (e.g., steroid based anti-inflammatory drugs)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Ronald Reagan UCLA Medical Center

Los Angeles, California, 90095, United States

Location

UCLA Medical Center, Santa Monica

Santa Monica, California, 90404, United States

Location

Related Publications (1)

  • Hwang B, Granger DA, Brecht ML, Doering LV. Cognitive behavioral therapy versus general health education for family caregivers of individuals with heart failure: a pilot randomized controlled trial. BMC Geriatr. 2022 Apr 5;22(1):281. doi: 10.1186/s12877-022-02996-7.

MeSH Terms

Conditions

DepressionCaregiver Burden

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorStress, Psychological

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Boyoung Hwang, PhD, RN

    University of California, Los Angeles

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

September 4, 2013

First Posted

September 10, 2013

Study Start

September 1, 2013

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

October 27, 2016

Record last verified: 2016-10

Locations