Evaluation of the Bone Mineral Density and Muscle Mass in Patients Post Coronary Artery Bypass Graft Surgery With Chronic Kidney Disease

NCT01932008 | Completed DMC

• 1 other identifier: FEMH-IRB-100110-F
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purposes of this study are: (1) to compare the body composition, physical activity, physical function, and quality of life between patients with and without CKD after CABG; and (2) to analyze the relationships among body composition, physical activity, and physical function in this population. It is expected that patients after CABG with CKD have the worse body composition, physical function, and quality of life than patients after CABG without CKD; and patients with higher physical activity levels have the better body composition, physical function, and quality of life.

Conditions

Coronary Artery Bypass Graft; Chronic Kidney Disease

Keywords

Coronary artery bypass grafting; Chronic kidney disease; Body composition; Physical activity; Physical function

Outcome Measures

Primary Outcomes (1)

• lean body mass and body fat

  All the subjects underwent dual-energy x-ray absorptiometry(DEXA) examination for body composition evaluation. The lean body mass and body fat were examined by DEXA.

  The participants were followed at one time points after operation in past 10 years

Secondary Outcomes (3)

• physical activity

  The participants were followed at one time points after operation in past 10 years

• physical function

  The participants were followed at one time points after operation in past 10 years

• quality of life

  The participants were followed at one time points after operation in past 10 years

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients who underwent CABG at the Department of Cardiovascular Center at Far-Eastern Memorial Hospital since January 2000 were selected for recruitment to this study.Thirty male patients after CABG with CKD and 30 matched controls were recruited (ages between 40-75 years old).

You may qualify if:

• patients undergoing CABG without valve surgery
• chronic kidney disease(matched group: without CKD)

You may not qualify if:

• heart transplantation or redo CABG
• amputation,
• cerebrovascular disease or any others disease with limbs dysfunction,
• lung deficit,
• cancer,
• cognitive disorders.

Sponsors & Collaborators

• Far Eastern Memorial Hospital: lead

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Motor Activity

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 27, 2013
• First Posted: August 30, 2013
• Study Start: May 1, 2012
• Primary Completion: June 1, 2013
• Study Completion: July 1, 2013
• Last Updated: August 30, 2013

Record last verified: 2012-04