Sublingual Administration of PPI
Sublingual Administration is More Fast Than Oral or IV Administration in PPI Dosing With Respect to Intragastric pH and Therapeutic Effectiveness: a Prospective, Randomized, Controlled Trial
1 other identifier
observational
60
1 country
1
Brief Summary
Compare 24-hour intragastric pH and therapeutic effectiveness of proton pump inhibitor (PPI) among different administration methods: per oral (PO), intravenous (IV), and sublingual (SL).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Aug 2013
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2013
CompletedFirst Submitted
Initial submission to the registry
August 19, 2013
CompletedFirst Posted
Study publicly available on registry
August 21, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedAugust 21, 2013
August 1, 2013
3 months
August 19, 2013
August 20, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Measure 24-hour intragastric pH
24 hours
Study Arms (3)
PO
administrated by per oral
IV
Administrated by intravenous
SL
administrated by sublingual
Eligibility Criteria
3 groups, each group with 20 subject with peptic ulcer ages between 20 to 75
You may qualify if:
- Patients with peptic ulcer disease
- Age: 20-75 years old
- Patients who submitted informed consent
You may not qualify if:
- Peptic ulcer disease with spurting and oozing
- Shock, hypotension, pregnancy
- Gastrointestinal malignancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
St.Mary's Hopspital of the Catholic University
Seoul, 150-713, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, PhD
Study Record Dates
First Submitted
August 19, 2013
First Posted
August 21, 2013
Study Start
August 1, 2013
Primary Completion
November 1, 2013
Study Completion
December 1, 2013
Last Updated
August 21, 2013
Record last verified: 2013-08