NCT01918787

Brief Summary

rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with autistic spectrum disorder

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at P25-P50 for phase_1

Timeline
Completed

Started Apr 2012

Typical duration for phase_1

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2012

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

August 2, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 8, 2013

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2015

Completed
Last Updated

August 8, 2013

Status Verified

April 1, 2012

Enrollment Period

3 years

First QC Date

August 2, 2013

Last Update Submit

August 7, 2013

Conditions

Autism

Outcome Measures

Primary Outcomes (1)

  • continuous performance test

    continuous performance test will be arranged before and after rTMS within one hour

    continuous performance test will be arranged before and after rTMS within one hour

Secondary Outcomes (1)

  • Yale-Brown Obsessive Compulsive Scale

    Yale-Brown Obsessive Compulsive Scale will be evaluated before and after rTMS within one week

Other Outcomes (1)

  • Autism Spectrum Quotient

    Autism Spectrum Quotient will be evaluated before and after rTMS within one week

Study Arms (1)

repetitive TMS

EXPERIMENTAL

repetitive TMS over dorsolateral prefrontal cortex, posterior superior temporal sulcus and inion as control

Device: repetitive TMS

Interventions

repetitive TMSDEVICE

rTMS (intermittent theta burst stimulation 1200)over posterior superior temporal sulcus,dorsolateral prefrontal cortex and inion as Sham control

repetitive TMS

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • adults with autistic spectrum disorder

You may not qualify if:

  • schizophrenia
  • bipolar affective disorder
  • major depressive disorder
  • any systemic disease especially epilepsy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chang Gung Memorial Hospital

Taoyuan District, Taiwan

RECRUITING

MeSH Terms

Conditions

Autistic Disorder

Condition Hierarchy (Ancestors)

Autism Spectrum DisorderChild Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Study Officials

  • Hsing-Chang Ni, MD

    Chang Gung Memorial Hospital at Linkou, Taiwan

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hsing Chang Ni, MD

CONTACT

886-3-3281200alanni0918@yahoo.com.tw

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 2, 2013

First Posted

August 8, 2013

Study Start

April 1, 2012

Primary Completion

April 1, 2015

Study Completion

April 1, 2015

Last Updated

August 8, 2013

Record last verified: 2012-04

Locations

TW(1)