NCT01915121

Brief Summary

The study main objectives are to enhance treatment decision making and improve quality of life and post-treatment health care among patients diagnosed with invasive bladder cancer. Bladder cancer (BL Ca) is the 5th most commonly diagnosed cancer in the US . BL Ca is more common among men than women and 90% of all patients are over the age of 55. Surgery to remove the bladder followed by one of three diversion techniques (i.e., ileal conduit, continent reservoir, and neobladder) is the standard therapy following invasive bladder cancer. The emotional, functional, physical, and social impact of invasive Bl Ca treatment on patients' QOL and adjustment can be devastating. This impact significantly varies by treatment option. Treatment decision making in for BL Ca is difficult at best and potentially susceptible to a number of cognitive and affective factors (e.g., patients' emotional reaction, values, and expectations). Thus, in addition to adjusting to a potential life-threatening disease, having to cope with uncertainty about the efficacy and outcomes of different treatment options adds to the overall distress and may impair effective decision-making. In spite of increasing efforts in health communication and patient education, no study has examined treatment decision making among invasive bladder patients or has provided an educational intervention to facilitate treatment decision making among this population. To this end, and guided by the Self-Regulation theory (SRT) that emphasizes the role of cognitive and emotional factors in decision making, we have designed and pilot tested the acceptability of a preliminary educational and training experiential intervention (ETE) to address this gap in the literature. The ETE intervention uses new and innovative educational strategies and methods to educate patients about their treatment options and to facilitate their treatment decision making.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 2, 2013

Completed
1 month until next milestone

Study Start

First participant enrolled

September 1, 2013

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2017

Completed
Last Updated

August 4, 2017

Status Verified

August 1, 2017

Enrollment Period

3.8 years

First QC Date

July 30, 2013

Last Update Submit

August 3, 2017

Conditions

Keywords

Bladder CancerInterventionEducationRandomized Controlled Trials

Outcome Measures

Primary Outcomes (16)

  • Decisional Regret Scale

    The intervention is designed to enhance treatment decision making.

    Baseline

  • Decisional Regret Scale

    The intervention is designed to enhance treatment decision making.

    1 month follow up

  • Decisional Regret Scale

    The intervention is designed to enhance treatment decision making.

    3 month follow up

  • Decisional Regret Scale

    The intervention is designed to enhance treatment decision making.

    6 month follow up

  • Decisional Self-Efficacy Scale

    The intervention is designed to enhance treatment decision making.

    Baseline

  • Decisional Self-Efficacy Scale

    The intervention is designed to enhance treatment decision making.

    1 month follow up

  • Decisional Self-Efficacy Scale

    The intervention is designed to enhance treatment decision making.

    3 month follow up

  • Decisional Self-Efficacy Scale

    The intervention is designed to enhance treatment decision making.

    6 month follow up

  • Treatment-related Values

    The intervention is designed to enhance treatment decision making.

    Baseline

  • Treatment-related Values

    The intervention is designed to enhance treatment decision making.

    1 month follow up

  • Treatment-related Values

    The intervention is designed to enhance treatment decision making.

    3 month follow up

  • Treatment-related Values

    The intervention is designed to enhance treatment decision making.

    6 month follow up

  • Decisional Regret Scale

    Bladder Cancer knowledge Scale The intervention is designed to enhance treatment decision making.

    Baseline

  • Decisional Regret Scale

    Bladder Cancer knowledge Scale The intervention is designed to enhance treatment decision making.

    1 month follow up

  • Decisional Regret Scale

    Bladder Cancer knowledge Scale The intervention is designed to enhance treatment decision making.

    3 month follow up

  • Decisional Regret Scale

    Bladder Cancer knowledge Scale The intervention is designed to enhance treatment decision making.

    6 month follow up

Secondary Outcomes (16)

  • quality of life

    Baseline

  • quality of life

    1 month follow up

  • quality of life

    3 month follow up

  • quality of life

    6 month follow up

  • post-surgical self-care

    Baseline

  • +11 more secondary outcomes

Study Arms (2)

Education Intervention

ACTIVE COMPARATOR

In this session, participant will be provided with information about bladder cancer treatment options, and training tools directly related to Bladder Cancer.

Behavioral: Education Intervention

Nutrition Intervention

PLACEBO COMPARATOR

In this session, participant will be provided with information about nutrition information directly related to bladder cancer recovery

Behavioral: Nutrition Intervention

Interventions

1-hour educational and training sessions. In this session, participant will be provided with information about bladder cancer treatment options, and training tools directly related to Bladder Cancer. In 4 to 5 days following the session, participants will be asked to schedule the time to talk about experience and how the intervention affects their treatment decision making and to answer some questions about the educational and training session they attended. Participants will then be called after 1-month, 3-month, and 6-month after their bladder cancer treatment to follow up.

Education Intervention

1-hour educational and training sessions. In this session, participant will be provided with nutrition information directly related to Bladder Cancer recovery. In 4 to 5 days following the session, participants will be asked to schedule the time to talk about experience and how the intervention affects their treatment decision making and to answer some questions about the educational and training session they attended. Participants will then be called after 1-month, 3-month, and 6-month after their bladder cancer treatment to follow up.

Nutrition Intervention

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • treatment of invasive Bladder Cancer a with cystectomy and one of the three major urinary diversion methods
  • English speaking
  • between the ages of 18 and 85
  • able and willing to provide informed consent
  • may have received neoadjuvant or adjuvant chemotherapy, radiation therapy, and immunotherapy (BCG)

You may not qualify if:

  • metastatic disease or cancer recurrence
  • presence of other primary cancers
  • no access to a telephone
  • Phase 2 (randomized-controlled-study)
  • \- treatment decision is made and /beginning/completion of treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States

Location

James J. Peters VA Medical Center

The Bronx, New York, 10468, United States

Location

MeSH Terms

Conditions

Urinary Bladder Neoplasms

Interventions

Early Intervention, EducationalDiet Therapy

Condition Hierarchy (Ancestors)

Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteNeoplasmsFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrinary Bladder DiseasesUrologic DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

Child Health ServicesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPreventive Health ServicesNutrition TherapyTherapeutics

Study Officials

  • Nihal E Mohamed, PhD

    Icahn School of Medicine at Mount Sinai

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 30, 2013

First Posted

August 2, 2013

Study Start

September 1, 2013

Primary Completion

June 30, 2017

Study Completion

June 30, 2017

Last Updated

August 4, 2017

Record last verified: 2017-08

Locations