Effects of Systemic Lidocaine on Postoperative Quality of Recovery After Robot-assisted Thyroidectomy
1 other identifier
interventional
90
1 country
1
Brief Summary
Systemic lidocaine infusion may improve the patients' recovery quality and chronic post surgical pain after robot-assisted thyroidectomy
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jul 2013
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2013
CompletedFirst Submitted
Initial submission to the registry
July 17, 2013
CompletedFirst Posted
Study publicly available on registry
July 25, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2015
CompletedJune 9, 2015
June 1, 2015
1.7 years
July 17, 2013
June 5, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Quality of recovery 40(QoR-40) score
Assessing change of the Quality of recovery 40(QoR-40) score between 24hours before and after operation
24hours after operation day
Secondary Outcomes (2)
Assessing the presence of chronic postsurgical pain(CPSP)
24hours after operation day
aspect and site of CPSP
24hours after operation day
Study Arms (2)
Group L
EXPERIMENTALIntravenous lidocaine infusion group
Group C
PLACEBO COMPARATORIntravenous normal saline infusion - control group
Interventions
In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.
Eligibility Criteria
You may qualify if:
- Age between 20-65
- ASA class I and II
- Thyroid cancer patients who are scheduled for elective robot-assisted thyroidectomy
You may not qualify if:
- Allergy to local anesthetics or contraindication to use of lidocaine
- Pregnancy
- Severe cardiovascular disease
- Renal failure
- Liver failure
- Neurologic and psychologic disease
- Chronic treatment with analgesics
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei universiy college of medicine
Seoul, 120-752, South Korea
Related Publications (1)
Choi KW, Nam KH, Lee JR, Chung WY, Kang SW, Joe YE, Lee JH. The Effects of Intravenous Lidocaine Infusions on the Quality of Recovery and Chronic Pain After Robotic Thyroidectomy: A Randomized, Double-Blinded, Controlled Study. World J Surg. 2017 May;41(5):1305-1312. doi: 10.1007/s00268-016-3842-1.
PMID: 27896411DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 17, 2013
First Posted
July 25, 2013
Study Start
July 1, 2013
Primary Completion
March 1, 2015
Study Completion
May 1, 2015
Last Updated
June 9, 2015
Record last verified: 2015-06