ICU Delirium: a One-week Snapshot of Burden Across the Eastern UK Region

NCT01902277 | Completed

• 1 other identifier: P01535
• Study Type: observational
• Target: 225
• Locations: 1 country
• Sites: 1

Brief Summary

ICU delirium negatively impacts on patient outcomes, as well as on resources and clinical workflow of the ICU. Effective healthcare resource planning requires reliable (i.e., multicentre) data that can inform on both of these. The purpose of this study was to determine the impact of ICU delirium in terms of both patients and beds. The study was carried out prospectively, over a one-week period, at adult ICUs comprising the Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN).

Conditions

Delirium

Keywords

Delirium; Intensive Care Unit; Critical illness

Outcome Measures

Primary Outcomes (1)

• Delirium prevalence

  Number of patients with at least one recorded delirium-positive result, over total number of patients recorded over study time frame. Delirium screening will be carried out using the CAM-ICU by local direct care clinicians in accordance with region-wide clinical delirium-screening guidelines.

  June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

Secondary Outcomes (11)

• Proportion of patient-days with delirium

  June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

• Median delirium duration

  June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

• Median days to transition to delirium

  June 25, 2012 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

• Patient age, by delirium status

  June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

• Patient gender, by delirium status

  June 25 (start of ICU day shift) to July 1, 2012 (end of ICU night shift)

Study Arms (1)

Adult critically ill patients

All adult patients treated within study time frame on Intensive Care Units across Norfolk, Suffolk, and Cambridgshire, UK

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult critically ill patients across eastern UK region

You may qualify if:

• Adult patients treated within study time frame on Intensive Care Units across Norfolk, Suffolk, and Cambridgshire, UK

Sponsors & Collaborators

• Papworth Hospital NHS Foundation Trust: lead
• Norfolk, Suffolk, and Cambridgeshire Critical Care Network (NSC CCN): collaborator

Study Sites (1)

Papworth Hospital NHS Foundation Trust

Cambridge, Cambridgeshire, CB23 5EF, United Kingdom

Location

MeSH Terms

Conditions

Delirium; Critical Illness

Condition Hierarchy (Ancestors)

Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; Disease Attributes; Pathologic Processes

Study Officials

• Alain Vuylsteke, MD

  Papworth Hospital NHS Foundation Trust

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 15, 2013
• First Posted: July 18, 2013
• Study Start: June 1, 2012
• Primary Completion: July 1, 2012
• Study Completion: July 1, 2012
• Last Updated: July 18, 2013

Record last verified: 2013-07

Locations

GB (1)