NCT01901822

Brief Summary

The hypothesis of this study is that coronally positioned tunnel with acellular dermal matrix using a continuous sling suture to secure both the graft and the flap will result in better percent root coverage compared to the continuous sling suturing technique to secure the graft and the flap separately.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2013

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 12, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 17, 2013

Completed
2 months until next milestone

Study Start

First participant enrolled

September 1, 2013

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

December 8, 2016

Status Verified

December 1, 2016

Enrollment Period

10 months

First QC Date

July 12, 2013

Last Update Submit

December 6, 2016

Conditions

Keywords

acellular dermal matrix

Outcome Measures

Primary Outcomes (1)

  • Percent root coverage

    The amount of root coverage will be measured and converted to a percent.

    6 months

Study Arms (2)

Sutured separately

ACTIVE COMPARATOR

The soft tissue and the allograft will each be sutured separately using a continuous sling suture.

Procedure: Sutured separately

Sutured together

EXPERIMENTAL

The soft tissue and the allograft will be sutured together using a continuous sling suture.

Procedure: Sutured together

Interventions

The soft tissue and the allograft will be sutured together using a continuous sling suture.

Sutured together

The soft tissue and the allograft will be sutured separately using a continuous sling suture.

Sutured separately

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • At least one Miller Class I or II mucogingival defect ≥ 3 mm (Miller 1985).
  • The mucogingival defect must be on a non-molar tooth.
  • Patients must be between ≥ 18 years of age.

You may not qualify if:

  • Patients with a known allergy to any of the materials that will be used in the study, including systemic antibiotics (tetracycline and doxycycline).
  • Patients requiring antibiotic prophylaxis.
  • Root surface restorations at the site of recession.
  • No detectable cemento-enamel junction.
  • Patients who fail to maintain oral hygiene levels of at least 80% plaque free surfaces.
  • Patients who are pregnant or lactating.
  • Patients who use tobacco products (smoking or smokeless tobacco).
  • Patients with alcohol abuse problems.
  • Patients undergoing long-term steroid therapy.
  • History of previous root coverage procedures, graft or guided tissue regeneration, on the test teeth.
  • Patients who fail to complete the informed consent form.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Graduate Periodontics Clinic University of Louisville

Louisville, Kentucky, 40202, United States

Location

Study Officials

  • Henry Greenwell, DMD

    University of Louisville

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 12, 2013

First Posted

July 17, 2013

Study Start

September 1, 2013

Primary Completion

July 1, 2014

Study Completion

July 1, 2014

Last Updated

December 8, 2016

Record last verified: 2016-12

Locations