NCT01900626

Brief Summary

This is a study comparing pain control utlilizing one or two epidural catheters, along with a hydromorphone PCA, for analgesia following surgery for correction of scoliosis.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2013

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

July 11, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 16, 2013

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
4.4 years until next milestone

Results Posted

Study results publicly available

May 8, 2019

Completed
Last Updated

May 8, 2019

Status Verified

April 1, 2019

Enrollment Period

1.4 years

First QC Date

July 11, 2013

Results QC Date

February 28, 2019

Last Update Submit

April 16, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain Scores With Activity

    The pain scores will be examined using the Numeric Rating Scale (NRS). NRS score ranges from 0-10. Higher score represents more pain/worse outcome

    72 hours

Secondary Outcomes (5)

  • Pain Scores at Rest

    72 hours

  • Opioid Usage

    72 hours

  • Functional Outcomes:The Pediatric Outcomes Data Collection Instrument (PODCI) Score

    3 months

  • Functional Outcomes: Scoliosis Research Society-22r (SRS-22r) Patient Questionnaire

    3 months

  • Functional Outcomes: The Owestry Disability Index(ODI)

    3 months

Study Arms (2)

single epidural catheter

ACTIVE COMPARATOR
Drug: epidural catheter

double epidural catheter

ACTIVE COMPARATOR
Drug: epidural catheter

Interventions

epidural catheter with 0.3% ropivacaine

double epidural cathetersingle epidural catheter

Eligibility Criteria

Age11 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Patients undergoing surgery via a posterior approach for AIS
  • Children ages 11-18
  • ASA physical status 1-2
  • Informed consent by legal guardian and assent by patient (for minors 11-17 years of age) or informed consent by subject (for patients 18 years of age)
  • Planned correction of at least 8 vertebral levels

You may not qualify if:

  • Patient refusal to participate
  • Patients on chronic narcotic medication
  • Allergy to standard of care drugs used in the study (Omnipaque, ropivacaine, hydromorphone, oxycodone, acetaminophen, gabapentin, ondansetron, nalbuphine or diphenhydramine, diazepam)
  • Coagulopathy
  • Pre-existing neurological deficit
  • Inability to use a Numerical Rating Scale (NRS: 0-10 patient self-reported score) for pain assessment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

American Family Children's Hospital

Madison, Wisconsin, 53792, United States

Location

Results Point of Contact

Title
Benjamin J. Walker, MD
Organization
University of Wisconsin School of Medicine and Public Health

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 11, 2013

First Posted

July 16, 2013

Study Start

July 1, 2013

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

May 8, 2019

Results First Posted

May 8, 2019

Record last verified: 2019-04

Locations