Trial for Femoroacetabular Impingement Treatment
FAIT
A Randomised Controlled Trial of Surgical Versus Non-surgical Treatment of Femoroacetabular Impingement
1 other identifier
interventional
120
1 country
2
Brief Summary
Femoroacetabular Impingement (FAI) describes a condition of the hip where additional bone results in the abutment of the femoral neck against the rim of the acetabulum. This gives rise to localised cartilage damage and pain, but also increases the risk of developing osteoarthritis. The purpose of this study is to compare the effectiveness of arthroscopic surgery versus physiotherapy and activity modification for the treatment of this condition.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jul 2013
Longer than P75 for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 14, 2013
CompletedStudy Start
First participant enrolled
July 1, 2013
CompletedFirst Posted
Study publicly available on registry
July 8, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2017
CompletedDecember 3, 2013
December 1, 2013
1.8 years
June 14, 2013
December 2, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Hip Outcome Score
Hip Outcome Score is a patient reported outcome measure
8 months post randomisation (approximately 6 months post intervention)
Secondary Outcomes (5)
Patient Reported Outcome Measures
Regular intervals up to 38 months post randomisation (approximately 3 years post intervention)
Morphological and Physiological MRI
Regular intervals up to 38 months post randomisation (approximately 3 years post intervention)
Hip Radiographs
Regular intervals up to 38 months post randomisation (approximately 3 years post intervention)
Serum and Urinary Biomarkers of Osteoarthritis
Regular intervals up to 38 months post randomisation (approximately 3 years post intervention)
Clinical Examination
Regular intervals up to 38 months post randomisation (approximately 3 years post intervention)
Study Arms (2)
Conservative treatment
ACTIVE COMPARATORPhysiotherapy and activity modification
Surgical treatment
ACTIVE COMPARATORArthroscopic treatment of femoroacetabular impingement
Interventions
Eligibility Criteria
You may qualify if:
- Symptomatic patients
- Age 18-60 years
- Clinical and radiological evidence of FAI
- Competent to consent
You may not qualify if:
- Prior hip surgery
- Established osteoarthritis (Kellgren-Lawrence \>/= 2)
- Hip dysplasia (Centre-Edge angle \< 20 degrees on radiograph)
- Completion of physiotherapy programme targeting FAI within past year
- Co-morbidities that mean surgical intervention is not possible/safe
- Contraindication to MRI
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Nuffield Orthopaedic Centre, Oxford University Hospitals Trust
Oxford, OX3 7LD, United Kingdom
Royal Berkshire Hospital
Reading, RG1 5AN, United Kingdom
Related Publications (3)
Palmer A, Fernquest S, Rombach I, Harin A, Mansour R, Dutton S, Dijkstra HP, Andrade T, Glyn-Jones S; FAIT Study Group. Medium-term results of arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of femoroacetabular impingement syndrome: a multi-centre randomised controlled trial. Br J Sports Med. 2025 Jan 2;59(2):109-117. doi: 10.1136/bjsports-2023-107712.
PMID: 39592214DERIVEDPalmer AJR, Ayyar Gupta V, Fernquest S, Rombach I, Dutton SJ, Mansour R, Wood S, Khanduja V, Pollard TCB, McCaskie AW, Barker KL, Andrade TJMD, Carr AJ, Beard DJ, Glyn-Jones S; FAIT Study Group. Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial. BMJ. 2019 Feb 7;364:l185. doi: 10.1136/bmj.l185.
PMID: 30733197DERIVEDPalmer AJ, Ayyar-Gupta V, Dutton SJ, Rombach I, Cooper CD, Pollard TC, Hollinghurst D, Taylor A, Barker KL, McNally EG, Beard DJ, Andrade AJ, Carr AJ, Glyn-Jones S. Protocol for the Femoroacetabular Impingement Trial (FAIT): a multi-centre randomised controlled trial comparing surgical and non-surgical management of femoroacetabular impingement. Bone Joint Res. 2014 Nov;3(11):321-7. doi: 10.1302/2046-3758.311.2000336.
PMID: 25431439DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sion Glyn-Jones, MA MBBS FRCS DPhil
University of Oxford
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 14, 2013
First Posted
July 8, 2013
Study Start
July 1, 2013
Primary Completion
April 1, 2015
Study Completion
July 1, 2017
Last Updated
December 3, 2013
Record last verified: 2013-12