Varicella-related Hospitalizations in Turkey

NCT01887496 | Completed

• 1 other identifier: VARICOMP
• Study Type: observational
• Target: 1,800
• Locations: 0 countries
• Sites: N/A

Brief Summary

Epidemiological information on varicella complications in children is essential for the development of appropriate immunization recommendations. Economic analyses of varicella immunization are sensitive to the costs of hospitalized cases, so there is a need to validate varicella-related hospitalization data in a country-specific manner. These data also provide a baseline for comparison with data collected after routine varicella immunization to evaluate the overall impact and cost-effectiveness of varicella immunization programs. Knowledge about the cause and incidence of varicella-related hospitalizations in Turkey is limited, center-specific and not sufficiently accurate. The aim of this multicenter study (VARICOMP) was to estimate the annual incidence of pediatric varicella-related hospitalization, describe the associated complications and estimate the annual mortality and economic cost of these cases.

Conditions

Chickenpox

Keywords

Varicella; Turkey; hospitalization; varicella vaccine

Outcome Measures

Primary Outcomes (1)

• Annual incidence of varicella-related hospitalization

  The primary goal of this study was to estimate the annual incidence of hospitalization resulting from varicella and to describe the associated complications.

  Hospitalization rate between 2008-2013 (up to 5 years)

Secondary Outcomes (1)

• The cost of varicella-related hospitalization in children.

  2008-2013 (up to 5 years)

Study Arms (1)

Chickenpox complications

Cases were identified by International Classification of Disease of the Tenth Revision (ICD-10) diagnostic codes for chickenpox infection or chickenpox-associated complications, if available.

Eligibility Criteria

• Age: 1 Day - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

0-18 years old hospitalized children due to varicella and -related complications

You may qualify if:

• years old hospitalized children due to varicella and -related complications
• Previously healthy or with chronic disease or conditions

Sponsors & Collaborators

• Eskisehir Osmangazi University: lead

MeSH Terms

Conditions

Chickenpox

Condition Hierarchy (Ancestors)

Varicella Zoster Virus Infection; Herpesviridae Infections; DNA Virus Infections; Virus Diseases; Infections

Study Officials

• Ener C Dinleyici, MD

  Eskisehir Osmangazi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor in Pediatrics

Study Record Dates

• First Submitted: November 12, 2012
• First Posted: June 27, 2013
• Study Start: September 1, 2010
• Primary Completion: October 1, 2012
• Study Completion: October 1, 2012
• Last Updated: July 28, 2017

Record last verified: 2017-07