NCT01884818

Brief Summary

The study includes two phases. In phase one the reliability of thoracic spine mobility measurements are studied in subjects with thoracic spine pain. In phase two the reliable measurements are used to measure the effects of thoracic spine manipulation in subjects with thoracic spine pain. The changes in pain is measured as well. In second phase the control group receives TNS treatment six times at home as a placebo so that the power of TNS is limited to very low level. The number of treatments are controlled as well as the time of treatment. The treatment group receives six manipulation treatments within 3 week period. The effects are measured immediately after the treatment weeks, and 3 and 8 week follow-up. Moreover the one year follow-up will be performed by mail questionnaire.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
78

participants targeted

Target at P50-P75 for not_applicable pain

Timeline
Completed

Started Aug 2011

Longer than P75 for not_applicable pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2011

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

February 25, 2013

Completed
4 months until next milestone

First Posted

Study publicly available on registry

June 24, 2013

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
14 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2017

Completed
Last Updated

August 21, 2017

Status Verified

August 1, 2017

Enrollment Period

6 years

First QC Date

February 25, 2013

Last Update Submit

August 16, 2017

Conditions

Keywords

Thoracic spine, pain, manipulation

Outcome Measures

Primary Outcomes (1)

  • Thoracic spine pain (Visual analogue scale)

    up to 49 week follow-up

Secondary Outcomes (1)

  • Thoracic spine mobility (computer controllod spine PA measurement, tape measurements, inclinometer)

    Baseline, after treatment, 3, 8, and 49 week follow-up

Other Outcomes (1)

  • Work absent

    Baseline, after treatment, 3, 8 and 49 week follow-up

Study Arms (2)

Manipulation

EXPERIMENTAL

Subjects will receive 6 manipulation treatments within 3 weeks period. The manipulated segments are determined individually in baseline assessment.

Other: Manipulation vs. TNS thoracic pain

TNS for thoracic spine

SHAM COMPARATOR

6 TNS treatments at home for 20min in limited power of devices in three weeks period.

Other: Manipulation vs. TNS thoracic pain

Interventions

ManipulationTNS for thoracic spine

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Thoracic spine pain,
  • years old

You may not qualify if:

  • Inflammatory spine disease,
  • previous surgery on thoracic spine area,
  • osteoporosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fysioteekki

Oulu, Finland

Location

Related Publications (1)

  • Takatalo J, Ylinen J, Pienimaki T, Hakkinen A. Intra- and inter-rater reliability of thoracic spine mobility and posture assessments in subjects with thoracic spine pain. BMC Musculoskelet Disord. 2020 Aug 10;21(1):529. doi: 10.1186/s12891-020-03551-4.

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jani Takatalo, MD

    University of Jyvaskyla

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Project expert

Study Record Dates

First Submitted

February 25, 2013

First Posted

June 24, 2013

Study Start

August 1, 2011

Primary Completion

August 1, 2017

Study Completion

August 15, 2017

Last Updated

August 21, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will share

Locations