Feasibility of Measurement of Optical Aberrations in Hyperopia by Using an Adaptive Optics Visual Simulator (AOVIS-I)

NCT01884805 | Terminated

• 1 other identifier: 12 483 03
• Study Type: interventional
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

The primary purpose of the protocol is to evaluate the adaptive optics visual simulator to measure optical aberrations in hyperopic eyes. The study hypotheses are the:

• Ability to measure optical aberrations in hypermetropia.
• Knowledge of optical aberrations of the eye hyperopic.
• To adapt therapeutic management in optical aberrations measured.

Conditions

Hyperopia

Keywords

Adaptive Optics Visual Simulator; Wavefront aberrometer; Optical Aberrations; Hyperopia

Outcome Measures

Primary Outcomes (1)

• Measurement of optical aberrations

  Feasibility of Measurement of optical aberrations in hyperopia by using an Adaptive Optics Visual Simulator AOVIS-I. Outcome measure is assessed during a consultation

  1 day (Participants will be followed for the duration of ophtalmology consultation)

Secondary Outcomes (2)

• Reproductibility of the measures

  1 day (Participants will be followed for the duration of ophtalmology consultation)

• Quantitative measurement of optical aberrations

  1 day (Participants will be followed for the duration of ophtalmology consultation)

Study Arms (1)

Monocular Adaptive Optics Visual Simulator (AOVIS-I)

OTHER

Device: Monocular Adaptive Optics Visual Simulator (AOVIS-I)

Interventions

Monocular Adaptive Optics Visual Simulator (AOVIS-I) DEVICE

The procedure is guided by the custom made software and its graphical user interface. The interface has been designed to be user-friendly, being very similar to the software usually managed by the clinicians in their daily professional practice. The complete procedure in one patient takes less than 5 minutes and is completely non-invasive. The optical measurements only involve the use of low power infrared laser and the visual testing is as simple for the patients as watching television and making responses.

Monocular Adaptive Optics Visual Simulator (AOVIS-I)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• hyperopic patients
• to be able to understand an information and give a consent
• affiliated to medical insurance

You may not qualify if:

• pregnant women or nursing mothers
• ocular infection
• keratitis
• restless patients

Sponsors & Collaborators

• University Hospital, Toulouse: lead
• Centre de Référence National du Kératocône: collaborator

Study Sites (1)

University Hospital, Toulouse

Toulouse, Midi-Pyrenees, 31059, France

Location

Related Publications (9)

• Fernandez EJ, Manzanera S, Piers P, Artal P. Adaptive optics visual simulator. J Refract Surg. 2002 Sep-Oct;18(5):S634-8. doi: 10.3928/1081-597X-20020901-27.

  PMID: 12361172 BACKGROUND

• Piers PA, Fernandez EJ, Manzanera S, Norrby S, Artal P. Adaptive optics simulation of intraocular lenses with modified spherical aberration. Invest Ophthalmol Vis Sci. 2004 Dec;45(12):4601-10. doi: 10.1167/iovs.04-0234.

  PMID: 15557473 BACKGROUND

• Piers PA, Manzanera S, Prieto PM, Gorceix N, Artal P. Use of adaptive optics to determine the optimal ocular spherical aberration. J Cataract Refract Surg. 2007 Oct;33(10):1721-6. doi: 10.1016/j.jcrs.2007.08.001.

  PMID: 17889766 BACKGROUND

• Manzanera S, Prieto PM, Ayala DB, Lindacher JM, Artal P. Liquid crystal Adaptive Optics Visual Simulator: Application to testing and design of ophthalmic optical elements. Opt Express. 2007 Nov 26;15(24):16177-88. doi: 10.1364/oe.15.016177.

  PMID: 19550905 BACKGROUND

• Villegas EA, Alcon E, Artal P. Optical quality of the eye in subjects with normal and excellent visual acuity. Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4688-96. doi: 10.1167/iovs.08-2316. Epub 2008 Jun 14.

  PMID: 18552387 BACKGROUND

• Fernandez EJ, Prieto PM, Artal P. Wave-aberration control with a liquid crystal on silicon (LCOS) spatial phase modulator. Opt Express. 2009 Jun 22;17(13):11013-25. doi: 10.1364/oe.17.011013.

  PMID: 19550501 BACKGROUND

• Fernandez EJ, Prieto PM, Artal P. Binocular adaptive optics visual simulator. Opt Lett. 2009 Sep 1;34(17):2628-30. doi: 10.1364/OL.34.002628.

  PMID: 19724513 BACKGROUND

• Perez GM, Manzanera S, Artal P. Impact of scattering and spherical aberration in contrast sensitivity. J Vis. 2009 Mar 25;9(3):19.1-10. doi: 10.1167/9.3.19.

  PMID: 19757958 BACKGROUND

• Bueno JM, Acosta E, Schwarz C, Artal P. Wavefront measurements of phase plates combining a point-diffraction interferometer and a Hartmann-Shack sensor. Appl Opt. 2010 Jan 20;49(3):450-6. doi: 10.1364/AO.49.000450.

  PMID: 20090810 BACKGROUND

MeSH Terms

Conditions

Hyperopia

Condition Hierarchy (Ancestors)

Refractive Errors; Eye Diseases

Study Officials

• François MALECAZE, PHD

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 24, 2013
• First Posted: June 24, 2013
• Study Start: March 1, 2013
• Primary Completion: September 1, 2013
• Study Completion: September 1, 2013
• Last Updated: July 16, 2019

Record last verified: 2019-07

Locations

FR (1)