NCT01882140

Brief Summary

The high incidence of burn injuries and mortality and morbidity as well as the high economic impact associated with this type of injury justifying the need to develop new technologies for the treatment of burn patients. Electrical stimulation for wound healing is a resource that has been increasingly used in routine physical therapists, but has the disadvantage of needing means of wet contact between the electrode and injury. The other resource used for therapeutic healing is conventional electrical stimulation of low intensity for capacitive field, a technique of physical therapy intervention not commercially available in Brazil. This new technology seems to have significant physiological effects in tissue repair and has been used for the treatment of chronic wounds which healed with difficulty. The objective is to analyze the effects of electrical stimulation of low intensity for capacitive field in healing skin burns. Patients from both genders aged over 18 years who have burns, will be evaluated and treated at the Emergency Unit of the Hospital of the Faculty of Medicine of Ribeirão Preto, University of São Paulo. The stimulation will be initiated within 24 hours after surgery to perform the graft and will be held daily for 60 minutes during the patient's stay or until complete healing of the skin. The electromagnetic field will be placed on the care of the burned area and / or the donor skin graft, not interfering with departmental procedures. Will be performed photographic record standardized wound by a digital camera, and then quantified by a computer program. Expected to reduce the period of hospitalization and thus lowering the cost of treatment, and the possibility of improving the quality of life of patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2013

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 28, 2013

Completed
4 days until next milestone

Study Start

First participant enrolled

June 1, 2013

Completed
19 days until next milestone

First Posted

Study publicly available on registry

June 20, 2013

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2015

Completed
Last Updated

June 20, 2013

Status Verified

June 1, 2013

Enrollment Period

1.4 years

First QC Date

May 28, 2013

Last Update Submit

June 17, 2013

Conditions

Keywords

burnswound healingmagnetic field therapy

Outcome Measures

Primary Outcomes (1)

  • clinical evaluation of the lesion

    The following parameters will be documented wound: wound appearance, capillarity, percentage of epithelialization, graft, signs of infection and sensitivity of the wound by burning to touch and clamping.

    Two years

Secondary Outcomes (2)

  • standard photographs records of the wounds and quantified by ImageJ ® software

    Two years

  • quantification of wounds photographs by digital software

    Two years

Other Outcomes (1)

  • assessment of health status of burned patients

    Two years

Study Arms (2)

Study Group

EXPERIMENTAL

Patients in the Study Group will receive daily treatment for 60 minutes. The treatment is initiated within 24 hours following surgery to achieve graft. Use of Electrical Stimulation by Capacitive Field was the only addition to the current standard of care of the Emergency Unit of HC-FMRP/USP. These Electrical Stimulation by Capacitive Field devices do not produce heat or cause any sensation in tissue. The equipment will produce an electrical stimulation of low intensity pulsed output (1.5 MHz, 1:4 duty cycles, 30mW). The electrodes consist of two metal plates (20x20cm) separated by an insulating material.

Other: Electrical Stimulation by Capacitive Field

Control Group (Sham devices)

PLACEBO COMPARATOR

Patients in the control group (Sham group) will receive the same treatment but the device remains off. Use of Electrical Stimulation by Capacitive Field was the only addition to the current standard of care of the Emergency Unit of HC-FMRP/USP.

Other: Electrical Stimulation by Capacitive Field Placebo Sham

Interventions

Eligibility Criteria

Age18 Years - 64 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • all patients admitted to the Burns Unit of Clinical Hospital, Faculty of Medicine of Ribeirão Preto / USP, in the period between September 2014 and June/2013.
  • greater than 18 years.
  • deep acute burn requiring excision and grafting

You may not qualify if:

  • patients who use medicines that may interfere with the process of tissue repair.
  • body mass index less than 16 kg / m²
  • older than 65 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Sao Paulo

Ribeirão Preto, São Paulo, 14049-900, Brazil

Location

Related Links

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

  • Rinaldo Roberto de Jesus Guirro, PHD

    University of Sao Paulo

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Rinaldo Roberto Jesus Guirro, PHD

CONTACT

Laboratory of physiotherapy resources

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PHD Professor

Study Record Dates

First Submitted

May 28, 2013

First Posted

June 20, 2013

Study Start

June 1, 2013

Primary Completion

November 1, 2014

Study Completion

February 1, 2015

Last Updated

June 20, 2013

Record last verified: 2013-06

Locations