NCT01879644

Brief Summary

Neurofeedback has proved to be effective in treating Attention deficit hyperactivity disorder (ADHD) in experimental settings. This study investigates whether neurofeedback can be used as a therapeutic intervention in regular outpatient care. The investigators compare high frequent neurofeedback with high frequent self-management therapy and suppose that both result in comparable effects.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Jan 2011

Longer than P75 for phase_2

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

May 28, 2013

Completed
21 days until next milestone

First Posted

Study publicly available on registry

June 18, 2013

Completed
4.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2018

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

November 15, 2016

Status Verified

November 1, 2016

Enrollment Period

7 years

First QC Date

May 28, 2013

Last Update Submit

November 14, 2016

Conditions

Keywords

ADHDNeurofeedbackSelf-ManagementParental PsychoeducationSocial Support

Outcome Measures

Primary Outcomes (2)

  • Core ADHD symptoms (inattention/hyperactivity/impulsivity) objectively assessed with the computer based Qb-Test (go-no-go-task with infrared camera)

    Children perform the Qb-Test: * T1 baseline diagnostic before therapy, 1 week * T2 post assessment after 36 therapy sessions, expected average of 12 weeks * T3 catamnestic measurement 6 months after T2 * T4 catamnestic measurement 12 months after T2

    Pre-Post-Change-Design; change for core symptoms from baseline to after 12 weeks, 6 and 12 months

  • Conners Psychopathology Scores

    Conners parents \& teacher rating scales: * T1 baseline diagnostic before therapy, 1 week * T2 post assessment after 36 therapy sessions, expected average of 12 weeks * T3 catamnestic measurement 6 months after T2 * T4 catamnestic measurement 12 months after T2

    Pre-Post-Change-Design; change from baseline to psychopathology scores after 12 weeks, 6 and 12 months

Secondary Outcomes (6)

  • Social Support

    Pre-Post-Change-Design; change from baseline to social support scores after 12 weeks, 6 and 12 months

  • Self-Concept

    Pre-Post-Change-Design; change from baseline to self-concept scores after 12 weeks, 6 and 12 months

  • Perceived Criticism

    Pre-Post-Change-Design; change from baseline to perceived criticism scores after 12 weeks, 6 and 12 months

  • Parental Stress (ESF)

    Pre-Post-Change-Design; change from baseline to parental stress scores after 12 weeks, 6 and 12 months

  • Cortisol

    Pre-Post-Change-Design; change from baseline to cortisol levels after 12 weeks, 6 and 12 month

  • +1 more secondary outcomes

Study Arms (4)

Neurofeedback with Psychoeducation (NF + PE)

ACTIVE COMPARATOR

Neurofeedback plus Parental Psychoeducation

Behavioral: NFBehavioral: PE

Self-Management with Psychoeducation (SM + PE)

ACTIVE COMPARATOR

Self-management + parental psychoeducation

Behavioral: SMBehavioral: PE

NF+PE and additional Social Support (SU)

ACTIVE COMPARATOR

Neurofeedback + parental psychoeducation enhanced with social support

Behavioral: NFBehavioral: PEBehavioral: SU

SM+PE and additional Social Support (SU)

ACTIVE COMPARATOR

Self-management + parental psychoeducation enhanced with social support

Behavioral: SMBehavioral: PEBehavioral: SU

Interventions

NFBEHAVIORAL
NF+PE and additional Social Support (SU)Neurofeedback with Psychoeducation (NF + PE)
SMBEHAVIORAL
SM+PE and additional Social Support (SU)Self-Management with Psychoeducation (SM + PE)
PEBEHAVIORAL
NF+PE and additional Social Support (SU)Neurofeedback with Psychoeducation (NF + PE)SM+PE and additional Social Support (SU)Self-Management with Psychoeducation (SM + PE)
SUBEHAVIORAL
NF+PE and additional Social Support (SU)SM+PE and additional Social Support (SU)

Eligibility Criteria

Age7 Years - 11 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • children with ADHD aged 7 to 11
  • full command of the German language.

You may not qualify if:

  • IQ below 80
  • Children with symptoms of:
  • inattention,
  • hyperactivity or
  • impulsivity due to other medical reasons such as:
  • hyperthyreosis,
  • autism,
  • epilepsy,
  • brain disorders and
  • any genetic or medical disorder associated with externalizing behavior that mimics ADHD.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Philipps-University Marburg, Department of Psychology, Clinical Child and Adolescent Psychology

Marburg, Hesse, 35037, Germany

RECRUITING

Related Publications (2)

  • Christiansen H, Reh V, Schmidt MH, Rief W. Slow cortical potential neurofeedback and self-management training in outpatient care for children with ADHD: study protocol and first preliminary results of a randomized controlled trial. Front Hum Neurosci. 2014 Nov 26;8:943. doi: 10.3389/fnhum.2014.00943. eCollection 2014.

  • Korfmacher AK, Hirsch O, Chavanon ML, Albrecht B, Christiansen H. Self-management training vs. neurofeedback interventions for attention deficit hyperactivity disorder: Results of a randomized controlled treatment study. Front Psychiatry. 2022 Aug 18;13:969351. doi: 10.3389/fpsyt.2022.969351. eCollection 2022.

Related Links

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Central Study Contacts

Hanna Christiansen, PhD

CONTACT

Winfried Rief, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr.

Study Record Dates

First Submitted

May 28, 2013

First Posted

June 18, 2013

Study Start

January 1, 2011

Primary Completion

January 1, 2018

Study Completion

December 1, 2018

Last Updated

November 15, 2016

Record last verified: 2016-11

Locations