NCT01879254

Brief Summary

For this human research, 17 treatment-refractory OCD patients who already received DBS implants for treatment refractory OCD between June 1998 and October 2007 will be included. New patients that complete the protocol on "refining the target for DBS in OCD" will be included in this follow-up study as well. They will be psychiatrically evaluated on regular bases: at least twice yearly in the years two to five after surgery, at least once a year for the years thereafter. The duration of this protocol is indefinite, but spans at least 10 years. The main aim of this study is to investigate the long-term effect of DBS in OCD patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2008

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2008

Completed
5.4 years until next milestone

First Submitted

Initial submission to the registry

June 12, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 17, 2013

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 5, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 5, 2015

Completed
Last Updated

July 10, 2024

Status Verified

July 1, 2024

Enrollment Period

7 years

First QC Date

June 12, 2013

Last Update Submit

July 9, 2024

Conditions

Keywords

obsessive compulsive disorder (OCD)deep brain stimulation (DBS)psychosurgerylong-term follow-up

Outcome Measures

Primary Outcomes (1)

  • Yale-Brown Obsessive Compulsive Scale (Y-BOCS)

    up to 10 years

Study Arms (1)

DBS for OCD

Device: Deep Brain Stimulation

Interventions

DBS for OCD

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients that have received DBS for OCD will be included in this study.

You may qualify if:

  • Patients who have received DBS implantation for the treatment of OCD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UZ Leuven

Leuven, Vlaams-Brabant, 3000, Belgium

Location

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Deep Brain Stimulation

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsSurgical Procedures, Operative

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 12, 2013

First Posted

June 17, 2013

Study Start

February 1, 2008

Primary Completion

February 5, 2015

Study Completion

February 5, 2015

Last Updated

July 10, 2024

Record last verified: 2024-07

Locations