NCT01878721

Brief Summary

The purpose of this study is to evaluate the value of positron emission tomography/computed tomography in various inflammatory conditions caused by bacterial infection or vasculitis. Glucose analog FDG is sensitive to detect inflammation foci but we hypothesize that other imaging agents such as PK11195 and Ga-citrate may have added value in certain applications.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
117

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2011

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

June 10, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 17, 2013

Completed
8.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2021

Completed
Last Updated

October 22, 2021

Status Verified

October 1, 2021

Enrollment Period

10.8 years

First QC Date

June 10, 2013

Last Update Submit

October 21, 2021

Conditions

InfectionVasculitis

Keywords

PET/CTinfectionvasculitis

Outcome Measures

Primary Outcomes (1)

  • Detection of infection or vasculitis in PET images

    within 1 week after starting the treatment

Secondary Outcomes (1)

  • Standardized uptake value of PET imaging agent at the site of infection or vasculitis

    within 1 week after starting the treatment

Study Arms (5)

Staphylococcus aureus bacteremia

PET/CT in patients with Staphylococcus aureus bacteremia

Radiation: PET/CT

Salmonella spp. bacteremia

PET/CT in patients with Salmonella spp. bacteremia

Radiation: PET/CT

Endocarditis

PET/CT in patients with infective endocarditis

Radiation: PET/CT

Pacemaker infection

PET/CT in patients with pacemaker infection

Radiation: PET/CT

Vasculitis

PET/CT in patients with vasculitis

Radiation: PET/CT

Interventions

PET/CTRADIATION

positron emission tomography/computed tomography

EndocarditisPacemaker infectionSalmonella spp. bacteremiaStaphylococcus aureus bacteremiaVasculitis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients of Turku University Hospital

You may qualify if:

  • Adults with
  • Staphylococcus aureus bacteremia or
  • Salmonella spp. bacteremia or
  • infective endocarditis or
  • infection of pacemaker or implantable cardioverter defibrillator or
  • vasculitis

You may not qualify if:

  • underage, pregnant, breastfeeding, handicapped or prisoner

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Turku University Hospital

Turku, FI-20521, Finland

Location

MeSH Terms

Conditions

InfectionsVasculitis

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

June 10, 2013

First Posted

June 17, 2013

Study Start

January 1, 2011

Primary Completion

October 1, 2021

Study Completion

October 1, 2021

Last Updated

October 22, 2021

Record last verified: 2021-10

Locations

FI(1)