NCT01876472

Brief Summary

Adult recipients of cochlear implants (CI) generally loose interest in listening to music. This may be due to the rather limited spectral resolution of CI. However, child CI-recipients, if offered the opportunity, like to listen to music. They participate actively in musical acitivities, such as singing, dancing or playing an instrument. Thus, there seems to be a fundamental difference in the music perception of people who receive CI as child or as adult. This study assesses music perception skills of child, teen and adult cochlear implant recipients in settings with simple tone sequences and in a more complex, melodious context.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2012

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

June 10, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 12, 2013

Completed
Last Updated

June 12, 2013

Status Verified

May 1, 2013

Enrollment Period

8 months

First QC Date

June 10, 2013

Last Update Submit

June 10, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Does the age at which a person receives a cochlear implant influence music perception skills?

    The test assesses wether cochlear implant carriers are able to hear the difference betweent two sequences of sounds, where in the second sequence on tone is different from the first sequence. If a difference is perceived, then the test assesses how big this difference has to be in order to be heard. The first and the second test are no more than six months apart; both times the same procedure is followed. The test is carried out with three age groups: 1. Children aged 3-10 years 2. Teenagers aged 11 - 14 years 3. Persons above 15 years

    Test and retest are taken within 6 months

Secondary Outcomes (1)

  • Do the results of the primary outcome measure depend on the tone sequence presented to the cochlear implant recipients?

    Test and retest are no more than 6 months apart

Other Outcomes (1)

  • How can the findings of the primary and the secondary outcome measure be used to improve music perception with existing cochlear implants?

    6 months

Study Arms (3)

Children aged 3 - 10 years

Assessment of music perception skills with cochlear implant recipients aged 3 - 10 years

Behavioral: Assessment of music perception skills

Teenagers aged 11 - 15 years

Assessment of music perception skills with cochlear implant recipients aged 11 - 15 years

Behavioral: Assessment of music perception skills

Adults aged 16 - 70 years

Assessment of music perception skills with cochlear implant recipients aged 16 - 70 years

Behavioral: Assessment of music perception skills

Interventions

A sequence of tones is presented to participants. Then the same sequence is presented again, with the 4th tone being one to six half tones different from the first sequence. Participants are asked to indicate when they hear a difference betweent the first and the second sequence.

Adults aged 16 - 70 yearsChildren aged 3 - 10 yearsTeenagers aged 11 - 15 years

Eligibility Criteria

Age3 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy CI recipients that receive their regular follow-ups in the ENT-clinic of the Zurich University Hospital.

You may qualify if:

  • Participants are uni- or bilateral CI recipients.
  • Participants are at least 3 years old.
  • Participants received CI one or more years before.
  • Participants are healthy.
  • Participation in the study is voluntary.
  • Participants and their legal custodians have read the information for participants at least one day prior to the test and given their written consent.

You may not qualify if:

  • Surgery for CI carried out less than one year before the test.
  • Children less than 3 years old.
  • Reduced cognitive capabilities due to old age.
  • Physical or mental handicaps.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich,

Zurich, Canton of Zurich, 8091, Switzerland

Location

Related Publications (15)

  • Svirsky MA, Robbins AM, Kirk KI, Pisoni DB, Miyamoto RT. Language development in profoundly deaf children with cochlear implants. Psychol Sci. 2000 Mar;11(2):153-8. doi: 10.1111/1467-9280.00231.

    PMID: 11273423BACKGROUND
  • Nicholas JG, Geers AE. Effects of early auditory experience on the spoken language of deaf children at 3 years of age. Ear Hear. 2006 Jun;27(3):286-98. doi: 10.1097/01.aud.0000215973.76912.c6.

    PMID: 16672797BACKGROUND
  • Svirsky MA, Teoh SW, Neuburger H. Development of language and speech perception in congenitally, profoundly deaf children as a function of age at cochlear implantation. Audiol Neurootol. 2004 Jul-Aug;9(4):224-33. doi: 10.1159/000078392.

    PMID: 15205550BACKGROUND
  • Fujita S, Ito J. Ability of nucleus cochlear implantees to recognize music. Ann Otol Rhinol Laryngol. 1999 Jul;108(7 Pt 1):634-40. doi: 10.1177/000348949910800702.

    PMID: 10435919BACKGROUND
  • Green T, Faulkner A, Rosen S. Spectral and temporal cues to pitch in noise-excited vocoder simulations of continuous-interleaved-sampling cochlear implants. J Acoust Soc Am. 2002 Nov;112(5 Pt 1):2155-64. doi: 10.1121/1.1506688.

    PMID: 12430827BACKGROUND
  • Peretz I, Hyde KL. What is specific to music processing? Insights from congenital amusia. Trends Cogn Sci. 2003 Aug;7(8):362-367. doi: 10.1016/s1364-6613(03)00150-5.

    PMID: 12907232BACKGROUND
  • Fitzsimons M, Sheahan N, Staunton H. Gender and the integration of acoustic dimensions of prosody: implications for clinical studies. Brain Lang. 2001 Jul;78(1):94-108. doi: 10.1006/brln.2000.2448.

    PMID: 11412018BACKGROUND
  • Shannon RV, Zeng FG, Kamath V, Wygonski J, Ekelid M. Speech recognition with primarily temporal cues. Science. 1995 Oct 13;270(5234):303-4. doi: 10.1126/science.270.5234.303.

    PMID: 7569981BACKGROUND
  • K. Gfeller, S. A. Witt, L. J. Spencer, J. Stordahl and B. Tomblin (1999), Musical Involvement and Enjoyment of Children Who Use Cochlear Implants, Volta Review, 100(4), pp. 213-233

    BACKGROUND
  • Mitani C, Nakata T, Trehub SE, Kanda Y, Kumagami H, Takasaki K, Miyamoto I, Takahashi H. Music recognition, music listening, and word recognition by deaf children with cochlear implants. Ear Hear. 2007 Apr;28(2 Suppl):29S-33S. doi: 10.1097/AUD.0b013e318031547a.

    PMID: 17496641BACKGROUND
  • Cooper WB, Tobey E, Loizou PC. Music perception by cochlear implant and normal hearing listeners as measured by the Montreal Battery for Evaluation of Amusia. Ear Hear. 2008 Aug;29(4):618-26. doi: 10.1097/AUD.0b013e318174e787.

    PMID: 18469714BACKGROUND
  • Sharma A, Dorman MF, Kral A. The influence of a sensitive period on central auditory development in children with unilateral and bilateral cochlear implants. Hear Res. 2005 May;203(1-2):134-43. doi: 10.1016/j.heares.2004.12.010.

    PMID: 15855038BACKGROUND
  • Looi V, She J. Music perception of cochlear implant users: a questionnaire, and its implications for a music training program. Int J Audiol. 2010 Feb;49(2):116-28. doi: 10.3109/14992020903405987.

    PMID: 20151886BACKGROUND
  • Gfeller K, Turner C, Mehr M, Woodworth G, Fearn R, Knutson JF, Witt S, Stordahl J. Recognition of familiar melodies by adult cochlear implant recipients and normal-hearing adults. Cochlear Implants Int. 2002 Mar;3(1):29-53. doi: 10.1179/cim.2002.3.1.29.

    PMID: 18792110BACKGROUND
  • Trehub SE, Cohen AJ, Thorpe LA, Morrongiello BA. Development of the perception of musical relations: semitone and diatonic structure. J Exp Psychol Hum Percept Perform. 1986 Aug;12(3):295-301. doi: 10.1037//0096-1523.12.3.295.

    PMID: 2943857BACKGROUND

Study Officials

  • Dorothe Veraguth, MD

    University Hospital Zurich, Clinic for Otorhinolaryngology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 10, 2013

First Posted

June 12, 2013

Study Start

November 1, 2011

Primary Completion

July 1, 2012

Study Completion

July 1, 2012

Last Updated

June 12, 2013

Record last verified: 2013-05

Locations