Comparison of Biomarkers of Stress in Emergency Physicians Working a 24-hour Shift or a 14-hour Night Shift - the JOBSTRESS Randomized Trial

NCT01874704 | Completed

• 2 other identifiers: CHU-01542009-A01309-48
• Study Type: interventional
• Target: 19
• Locations: 1 country
• Sites: 1

Brief Summary

A stressful state can lead to symptoms of mental exhaustion, physical fatigue, medical errors, and also increase coronary heart disease. Emergency physicians subjectively complain of stress related to changes in work shifts. Several potential biomarkers of stress have been described, but never investigated in emergency physician, who may represent a good model of stress due to the complex interplay between stress (life-and-death emergencies, which is the defining characteristic of their job), lack of sleep and fatigue due to repeated changes in shifts.The aim of this study was to compare biomarkers in emergency physicians working a 24-hour shift (24hS) or a 14-hour night shift (14hS), and in those working a control day (clerical work on return from leave). We also followed these markers three days following each shift (D3/24hS and D3/14hS).

Conditions

Biomarkers of Stress in Emergency Physicians

Keywords

Stress, occupation, biomarkers, emergency, physicians

Outcome Measures

Primary Outcomes (1)

• Putative biomarkers of stress include heart rate variability (urinary and salivary steroids, saliva immunogobulin A, ...)

  These biomarkers will be collected in emergency physicians

  at day 1

Secondary Outcomes (5)

• perceived stress measured using visual analog scale (VAS)

  at day 1

• perceived fatigue (VAS)

  at day 1

• sleep duration (hours)

  at day 1

• sleep quality (VAS)

  at ady 1

• workload within the emergency department during the shifts

  at day 1

Study Arms (1)

biomarkers of stress

OTHER

Comparison of biomarkers of stress in emergency physicians working a 24-hour shift or a 14-hour night shift

Behavioral: Comparison of biomarkers of stress

Interventions

Comparison of biomarkers of stress BEHAVIORAL

biomarkers of stress

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• emergency physician

You may not qualify if:

• endocrine disease, pregnancy, recent extraprofessional deleterious life event (such as death of a near relative, divorce), any current illness, drugs used to modulate inflammatory diseases (corticosteroids, anti-inflammatory drugs, immunomodulatory drugs), or any drugs with a chronotropic effect taken over the previous six months (beta blockers, diltiazem, verapamil, anxiolytics or antidepressants).

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead
• Association des Médecins des Urgences de Clermont-Ferrand: collaborator
• Université d'Auvergne: collaborator

Study Sites (1)

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

Location

Related Publications (1)

• Dutheil F, Marhar F, Boudet G, Perrier C, Naughton G, Chamoux A, Huguet P, Mermillod M, Saadaoui F, Moustafa F, Schmidt J. Maximal tachycardia and high cardiac strain during night shifts of emergency physicians. Int Arch Occup Environ Health. 2017 Aug;90(6):467-480. doi: 10.1007/s00420-017-1211-5. Epub 2017 Mar 7.

  PMID: 28271382 DERIVED

MeSH Terms

Conditions

Emergencies

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Alain CHAMOUX

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 24, 2013
• First Posted: June 11, 2013
• Study Start: April 1, 2010
• Primary Completion: September 1, 2010
• Study Completion: September 1, 2011
• Last Updated: June 11, 2013

Record last verified: 2013-06

Locations

FR (1)