NCT01862107|Terminated
Study Stopped
Study terminated due to limited resources and declining participation.
Loading search results
Sponsor study identifier
Secondary identifiers
observational
51
1 country
1
Study Start
July 29, 2013
Actual (reported)Primary Completion
April 23, 2025
Actual (reported)Study Completion
April 23, 2025
Actual (reported)Background: \- Cerebrospinal fluid (CSF) is the liquid around the brain and spinal cord. Many diseases can only be diagnosed by examining the CSF. A lumbar puncture is used to collect and test CSF. Once someone is already having a lumbar puncture, a small extra amount of CSF can be collected at the same time. This fluid can be used to study brain, nerve, and related health issues. Researchers want to collect CSF and blood samples from people who are scheduled to have a lumbar puncture. Objectives: \- To collect cerebrospinal fluid and blood samples from individuals who are having a lumbar puncture. Eligibility: \- Individuals between 2 and 100 years of age who are scheduled to have a lumbar puncture for clinical or research purposes. Design:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 23, 2025
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 22, 2013
Actual (reported)May 24, 2013
Actual (reported)July 29, 2013
Actual (reported)April 23, 2025
Actual (reported)April 23, 2025
Actual (reported)The primary objective of this study is to create a repository of CSF and matched serum and plasma samples.
Repository of CSF and matched blood.
ongoing
Any healthy volunteer getting a lumbar puncture done for either clinical care or research purposes.
Any patient getting a lumbar puncture done for either clinical care or research purposes.
The study is a collection of additional CSF from any patient getting a lumbar puncture done for either clinical care or research purposes.
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Kuntz KM, Kokmen E, Stevens JC, Miller P, Offord KP, Ho MM. Post-lumbar puncture headaches: experience in 501 consecutive procedures. Neurology. 1992 Oct;42(10):1884-7. doi: 10.1212/wnl.42.10.1884.
Silverberg GD, Heit G, Huhn S, Jaffe RA, Chang SD, Bronte-Stewart H, Rubenstein E, Possin K, Saul TA. The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type. Neurology. 2001 Nov 27;57(10):1763-6. doi: 10.1212/wnl.57.10.1763.
Avindra Nath, M.D.
National Institute of Neurological Disorders and Stroke (NINDS)
51 participants (actual enrollment reported by the registry).
First Submitted
May 22, 2013
First Posted
May 24, 2013
Study Start
July 29, 2013
Actual (reported)Primary Completion
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome
Contact the study team to confirm eligibility.
Ebinger F, Kosel C, Pietz J, Rating D. Headache and backache after lumbar puncture in children and adolescents: a prospective study. Pediatrics. 2004 Jun;113(6):1588-92. doi: 10.1542/peds.113.6.1588.
April 23, 2025
Actual (reported)Study Completion
April 23, 2025
Actual (reported)Last Updated
April 24, 2025
Record last verified: 2024-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: