NCT01853904

Brief Summary

Bronchoalveolar lavage (BAL) is a common technique among pulmonologists. Its goal is to collect cells from alveolar units. This is done by wedging a flexible bronchoscope in a bronchus, instilling saline, and removing the saline via suction. Two techniques are currently used for suctioning: syringe based and channel suction. The investigators concern is that channel suction creates too much force and there is collapsing of the airways which results in decreased fluid removal as well as cell sampling. The investigators propose that syringe based suctioning will not only return more of the instilled fluid but also more cells from the alveoli.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2012

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

April 5, 2013

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 15, 2013

Completed
17 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2013

Completed
Last Updated

January 7, 2014

Status Verified

January 1, 2014

Enrollment Period

11 months

First QC Date

April 5, 2013

Last Update Submit

January 6, 2014

Conditions

Bronchoscopy

Keywords

BronchoscopyBALSuction

Outcome Measures

Primary Outcomes (1)

  • Efficacy of Syringe Suction versus Channel Suction to retrieve volume

    24 hours

Secondary Outcomes (1)

  • Efficacy of Syringe suction versus Channel suction to retrieve alveolar cells

    24 hours

Study Arms (2)

Channel Suction first

OTHER

This arm is for patients who will receive channel suction first to obtain the specimen then syringe suction to obtain the specimen.

Procedure: Bronchoscopy/ BAL with Channel SuctionProcedure: Bronchoscopy/BAL with Syringe Suction

Syringe Suction first

OTHER

This arm is for patients who will receive syringe suction first to obtain the specimen then channel suction to obtain the specimen.

Procedure: Bronchoscopy/ BAL with Channel SuctionProcedure: Bronchoscopy/BAL with Syringe Suction

Interventions

Bronchoscopy/ BAL with Channel SuctionPROCEDURE

The wall suction used for the channel suction will be set at 80 mm Hg. This arm is for patients who will receive channel suction first to obtain the specimen then syringe suction to obtain the specimen.

Channel Suction firstSyringe Suction first
Bronchoscopy/BAL with Syringe SuctionPROCEDURE

Syringe based suctioning will be performed with 20mL syringe.

Channel Suction firstSyringe Suction first

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Bronchoscopy scheduled

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

OUHSC

Oklahoma City, Oklahoma, 73104, United States

Location

MeSH Terms

Interventions

Bronchoscopy

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Respiratory SystemDiagnostic Techniques and ProceduresDiagnosisEndoscopyDiagnostic Techniques, SurgicalMinimally Invasive Surgical ProceduresSurgical Procedures, OperativePulmonary Surgical ProceduresThoracic Surgical Procedures

Study Officials

  • Brent Brown, MD

    OUHSC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 5, 2013

First Posted

May 15, 2013

Study Start

July 1, 2012

Primary Completion

June 1, 2013

Study Completion

August 1, 2013

Last Updated

January 7, 2014

Record last verified: 2014-01

Locations

US(1)