NCT01853189

Brief Summary

Asthma is a highly prevalent chronic disease in children. Complementary and Alternative Medicine research on asthma showed a potential effect on pediatric patients. Studies looking at the effect of Osteopathic Manipulative Treatment seems to reveal positive results. The aim of study is to further explore the role of OMT on asthma in a pediatric population.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Nov 2014

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 10, 2013

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 14, 2013

Completed
1.5 years until next milestone

Study Start

First participant enrolled

November 1, 2014

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

April 25, 2014

Status Verified

April 1, 2014

Enrollment Period

10 months

First QC Date

May 10, 2013

Last Update Submit

April 24, 2014

Conditions

Keywords

pediatricsasthmaosteopathic manipulative treatment

Outcome Measures

Primary Outcomes (1)

  • Difference in Forced expiratory volume in the 1st second (FEV1) before and after OMT

    Participants will be assessed at entry, after 3 and 6 months.

Secondary Outcomes (5)

  • Difference in fractional exhaled nitric oxide (FeNO) before and after OMT

    Participants will be assessed at entry, after 3 and 6 months.

  • Difference in percentage of hemoglobin saturation before and after OMT

    Participants will be assessed at entry, after 3 and 6 months.

  • Difference in Pediatric Asthma Quality of Life Questionnaire (PAQOL) before and after OMT

    Participants will be assessed at entry, after 3 and 6 months.

  • Differences in the number, type and quality of somatic dysfunctions

    Participants will be assessed at entry, after 3 and 6 months

  • Difference in peak expiratory flow (PEF) before and after OMT

    Participants will be assessed at entry, after 3 and 6 months.

Study Arms (2)

OMT + Usual Care

OTHER
Other: OMT + Usual Care

Usual Care

OTHER
Other: Usual Care

Interventions

patients from this group received 6 sessions of OMT

OMT + Usual Care

patients from control group received standard care + osteopathic evaluation only, according to the same schedule of the study group

Usual Care

Eligibility Criteria

Age5 Years - 14 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • children with asthma age between 5 and 14

You may not qualify if:

  • associated co-morbities surgical patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Santo Spirito Hospital

Pescara, Abruzzo, 65100, Italy

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Central Study Contacts

Francesco Cerritelli, MS, DO

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 10, 2013

First Posted

May 14, 2013

Study Start

November 1, 2014

Primary Completion

September 1, 2015

Study Completion

December 1, 2015

Last Updated

April 25, 2014

Record last verified: 2014-04

Locations