NCT01851876

Completed

Endometrial Injury and Single Embryo Transfer

Karadeniz Technical University Source

Karadeniz Technical University

ClinicalTrials.gov

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Other study identifiers

Sponsor study identifier

2011/20

Study Type

interventional

Actual enrollment (reported)

118

Locations

0 countries

Sites

N/A

Timeline

Study Start

September 2010

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

April 2011

Actual (reported)

Study Completion

April 2011

Actual (reported)

Brief Summary

Endometrial injury increases clinical pregnancy rate in normoresponder patients undergoing long agonist protocol intracytoplasmic sperm injection cycles with single embryo transfer.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 118 participants
Study completion date: April 2011
Actual (reported)
Listed locations: 0 countries · 0 sites

Trial Relationships

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Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
September 2010
Date type not reported
This date has not been verified as actual or estimated.
Primary Completion
April 2011
Actual (reported)
Study Completion
April 2011
Actual (reported)
First Submitted
April 26, 2013
Actual (reported)
First Posted
May 13, 2013
Actual (reported)
Results Posted
July 1, 2013
Actual (reported)

Last Updated: July 1, 2013
Status Verified: May 2013
Results QC Date: May 11, 2013
Last Update Submitted: May 11, 2013

Conditions

Primary Infertility

Outcome Measures

Primary Outcomes (2)

Clinical Pregnancy Rate
up to 6 months
Clinical Pregnancy Rate
4 months

Study Arms (2)

Endometrial injury

EXPERIMENTAL

The patients in this group will be subjected to endometrial injury procedure in preceding IVF cycle.

Device: Endometrial injury

No endometrial injury

NO INTERVENTION

The patients in this group will not be subjected to endometrial injury procedure in presiding IVF cycle. The patients will be stimulated with standard IVF protocol.

Interventions

Endometrial injuryDevice

Endometrial injury with Endometrial Suction Curette (pipelle) will be performed.

Endometrial injury

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 35 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

woman age under 35 years
history of primary infertility

Sponsors & Collaborators

Karadeniz Technical University
Otherlead

Limitations and Caveats

No limitations.

Results Point of Contact

Title: Dr. Suleyman Guven, Director of clinical trial
Organization: Karadeniz Technical University, School of Medicine, Dept Obs and Gyn.

Study Officials

Suleyman Guven
Karadeniz Technical University
PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee: Yes

Enrollment

118 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NON RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assoc. Prof.

Study Record Dates

First Submitted

April 26, 2013

First Posted

May 13, 2013

Study Start

September 2010

Date type not reported

This date has not been verified as actual or estimated.

NCT02863198

Endometrial Injury for Unexplained Infertility

Not ApplicableCompleted

NCT03220503

Effect of Endometrial Injury Before Frozen Embryo Transfer on Pregnancy Rate

Phase 4Unknown

NCT02492451

Endometrial Injury Versus Luteal Phase Support in Intrauterine Insemination Cycles

Not ApplicableTerminated

NCT02704936

Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination

Withdrawn

NCT05903638

A Pilot RCT: the Impact of a Virtual MBSR Course on Women With Primary Infertility

Not ApplicableUnknown

NCT01132144

Endometrial Injury for Assisted Reproduction

Phase 3Terminated

normoresponder (antral follicle count 5-10 in one ovary in early follicular phase

having grade I or II embryos for transfer

agree to undergo endometrial biopsy during the COH cycle. All patients were stimulated with luteal phase long protocol.

You may not qualify if:

endocrinopathies (including diabetes mellitus, hyperprolactinemia, Cushing's disease, and congenital adrenal hyperplasia), any systemic disease, collagen disorder, hypercholesterolemia, sickle cell anemia, and a history of neoplasm; -high risk for or history of OHSS
using any concurrent medication (e.g., insulin-sensitizing drugs, and GnRH antagonists)
patients who did not proceed to follicle retrieval
severe male infertility requiring TESA/TESA
mullerian tract anomalies
a history of endometrial instrumentation or surgery within a month of the study
not agree to undergo endometrial biopsy during the COH cycle.

Contact the study team to confirm eligibility.

Primary Completion

April 2011

Actual (reported)

Study Completion

April 2011

Actual (reported)

Last Updated

July 1, 2013

Results First Posted

July 1, 2013

Record last verified: 2013-05

Source record

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Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01851876
Data provider: ClinicalTrials.gov
Source updated: 2013-07-01
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:24:41 UTC

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Results Posted

Conditions

Outcome Measures

Primary Outcomes (2)

Study Arms (2)

Endometrial injury

No endometrial injury

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Limitations and Caveats

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record